EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
3.4.21.B26 | proprotein convertase 5 |
A-549 cell |
- |
675967 |
3.4.21.B28 | fibroblast activation protein alpha subunit |
A-549 cell |
- |
753899 |
3.4.21.B41 | kallikrein 10 |
A-549 cell |
lung adenocarcinoma cell line |
707999 |
3.4.21.B6 | prostasin |
A-549 cell |
- |
671251 |
3.4.21.B60 | transmembrane protease serine 2 |
A-549 cell |
- |
764554 |
3.4.22.52 | calpain-1 |
A-549 cell |
- |
708761 |
3.4.22.52 | calpain-1 |
A-549 cell |
protein phosphatase 2A functions as a physiological calpain phosphatase to directly dephosphorylate mu-calpain, which leads to decreased calpain activity and suppression of migration and invasion of human lung cancer cells |
680713 |
3.4.22.53 | calpain-2 |
A-549 cell |
- |
707902, 707980 |
3.4.22.55 | caspase-2 |
A-549 cell |
- |
732068, 732733 |
3.4.22.55 | caspase-2 |
A-549 cell |
expression of c-Myc and caspase-2 are crucial for cytochrome c release from mitochondria during cytotoxic stress. Caspase-2 is important for cytosolic Bax to integrate into the outer mitochondrial membrane |
687708 |
3.4.22.55 | caspase-2 |
A-549 cell |
human lung adenocarcinoma cell |
665247 |
3.4.22.56 | caspase-3 |
A-549 cell |
- |
698258 |
3.4.22.57 | caspase-4 |
A-549 cell |
- |
677484 |
3.4.22.61 | caspase-8 |
A-549 cell |
- |
697284, 698258, 708818 |
3.4.24.23 | matrilysin |
A-549 cell |
- |
-, 707049, 733641, 733800 |
3.4.24.35 | gelatinase B |
A-549 cell |
- |
707964, 708070 |
3.4.24.63 | meprin B |
A-549 cell |
- |
755466 |
3.4.24.79 | pappalysin-1 |
A-549 cell |
- |
735072 |
3.4.24.86 | ADAM 17 endopeptidase |
A-549 cell |
- |
752817, 754375 |
3.4.24.B4 | matrix metalloproteinase-13 |
A-549 cell |
- |
713548 |
3.4.24.B7 | matrix metalloproteinase-26 |
A-549 cell |
- |
713160, 720479 |
3.4.24.B7 | matrix metalloproteinase-26 |
A-549 cell |
lung carcinoma, gene expression |
650768 |
3.4.24.B9 | ADAM9 endopeptidase |
A-549 cell |
- |
719607 |
3.4.25.1 | proteasome endopeptidase complex |
A-549 cell |
- |
711074, 733663 |
3.5.1.105 | chitin disaccharide deacetylase |
A-549 cell |
- |
754966 |
3.5.1.2 | glutaminase |
A-549 cell |
- |
734818 |
3.5.1.2 | glutaminase |
A-549 cell |
kidney-type glutaminase GLS1 |
720930 |
3.5.1.88 | peptide deformylase |
A-549 cell |
- |
733571, 757712 |
3.5.1.92 | pantetheine hydrolase |
A-549 cell |
- |
755957 |
3.5.1.98 | histone deacetylase |
A-549 cell |
- |
695508, 696050, 696610, 699429, 704641, 711088, 712434 |
3.5.3.15 | protein-arginine deiminase |
A-549 cell |
- |
711811 |
3.6.1.13 | ADP-ribose diphosphatase |
A-549 cell |
- |
655991 |
3.6.1.23 | dUTP diphosphatase |
A-549 cell |
- |
758298 |
3.6.1.75 | diacylglycerol diphosphate phosphatase |
A-549 cell |
- |
679998 |
3.6.1.9 | nucleotide diphosphatase |
A-549 cell |
- |
756660 |
3.6.5.2 | small monomeric GTPase |
A-549 cell |
- |
687915 |
4.1.1.17 | ornithine decarboxylase |
A-549 cell |
lung cancer cell line |
677292 |
4.1.1.17 | ornithine decarboxylase |
A-549 cell |
lung carcinoma cells |
681869 |
4.1.1.84 | D-dopachrome decarboxylase |
A-549 cell |
lung adenocarcinoma cell line |
693465 |
4.1.2.27 | sphinganine-1-phosphate aldolase |
A-549 cell |
- |
726675 |
4.2.1.3 | aconitate hydratase |
A-549 cell |
- |
696168 |
4.2.99.18 | DNA-(apurinic or apyrimidinic site) lyase |
A-549 cell |
- |
706019, 748653 |
4.3.2.9 | gamma-glutamylcyclotransferase |
A-549 cell |
- |
705761 |
4.4.1.1 | cystathionine gamma-lyase |
A-549 cell |
- |
710226 |
4.4.1.5 | lactoylglutathione lyase |
A-549 cell |
- |
710151 |
4.6.1.2 | guanylate cyclase |
A-549 cell |
- |
694121 |
5.1.3.17 | heparosan-N-sulfate-glucuronate 5-epimerase |
A-549 cell |
- |
714635 |
5.3.4.1 | protein disulfide-isomerase |
A-549 cell |
- |
765061 |
5.3.99.3 | prostaglandin-E synthase |
A-549 cell |
- |
667959, 678094, 690622, 693577, 693823, 706521, 714421, 714468, 715856, 715865, 748441, 748846 |
5.3.99.5 | thromboxane-A synthase |
A-549 cell |
- |
702474 |
5.3.99.5 | thromboxane-A synthase |
A-549 cell |
an adenocarcinoma cell line |
728292 |
5.6.1.4 | minus-end-directed kinesin ATPase |
A-549 cell |
- |
733397 |
5.6.2.1 | DNA topoisomerase |
A-549 cell |
- |
691321, 691729, 702564, 702620, 705047, 714463, 727417, 747038, 747693, 747698 |
5.6.2.1 | DNA topoisomerase |
A-549 cell |
human lung cancer cells |
693067 |
5.6.2.1 | DNA topoisomerase |
A-549 cell |
lung cancer cell |
691619 |
5.6.2.1 | DNA topoisomerase |
A-549 cell |
nonsmall cell lung cancer cell line |
693543 |
5.6.2.2 | DNA topoisomerase (ATP-hydrolysing) |
A-549 cell |
- |
662925, 678594, 691220, 702620, 705649, 716400, 727171, 747038, 747701, 750475 |
6.1.1.10 | methionine-tRNA ligase |
A-549 cell |
- |
745956 |
6.1.1.20 | phenylalanine-tRNA ligase |
A-549 cell |
lung carcinoma cell line |
649540 |
6.1.1.4 | leucine-tRNA ligase |
A-549 cell |
LARS1 is over-expressed in lung cancer cell line A549 |
692229 |
6.1.1.6 | lysine-tRNA ligase |
A-549 cell |
- |
745950 |
6.2.1.1 | acetate-CoA ligase |
A-549 cell |
- |
744656 |
6.3.2.17 | tetrahydrofolate synthase |
A-549 cell |
- |
691823 |
6.3.2.2 | glutamate-cysteine ligase |
A-549 cell |
- |
703592, 715088 |
6.3.2.3 | glutathione synthase |
A-549 cell |
- |
703592 |
6.3.2.6 | phosphoribosylaminoimidazolesuccinocarboxamide synthase |
A-549 cell |
- |
745942 |
6.3.4.21 | nicotinate phosphoribosyltransferase |
A-549 cell |
weak expression |
745944 |
6.4.1.2 | acetyl-CoA carboxylase |
A-549 cell |
- |
706433 |
7.1.1.1 | proton-translocating NAD(P)+ transhydrogenase |
A-549 cell |
- |
765163 |
7.1.2.2 | H+-transporting two-sector ATPase |
A-549 cell |
- |
748800 |
7.2.2.13 | Na+/K+-exchanging ATPase |
A-549 cell |
- |
711156, 712805 |
7.2.2.13 | Na+/K+-exchanging ATPase |
A-549 cell |
type II lung adenocarcinoma epithelial cells |
711712 |
7.2.2.8 | P-type Cu+ transporter |
A-549 cell |
- |
752318 |
7.6.2.1 | P-type phospholipid transporter |
A-549 cell |
- |
720146 |