EC Number |
Application |
Reference |
---|
2.7.11.11 | drug development |
recombinant PKA can be mutated to resemble Akt/PKB, which cannot be easily recombinantly expressed, mutant PKA can be used as surrogate enzyme for Akt/PKB in drug design |
661759 |
2.7.11.11 | drug development |
the enzyme represents an attractive target for the development of anti-malarial drugs |
723339 |
2.7.11.11 | medicine |
activation of protein kinase A by elevation of the intracellular cAMP level inhibits skeletal myogenesis |
694153 |
2.7.11.11 | medicine |
cAMP-dependent protein kinase acts synergistically with exchange protein directly activated by cAMP to promote adipogenesis |
694155 |
2.7.11.11 | medicine |
hepatitis C virus infection activates PKA in a cAMP-dependent manner to promote virus release and transmission |
693925 |
2.7.11.11 | medicine |
PKA is a target for the therapeutic treatment of Alzheimer's disease and other tauopathies |
662302 |