1.1.1.141 15-hydroxyprostaglandin dehydrogenase (NAD+) adrenal cortex both 15-hydroxyprostaglandin dehydrogenase mRNA and protein levels are significantly higher in kidney cortex than in papilla. Enzyme is mainly localized to the tubular epithelial cells in kidney cortex and outer medulla 684372 1.1.1.145 3beta-hydroxy-DELTA5-steroid dehydrogenase adrenal cortex - 668413 1.1.1.145 3beta-hydroxy-DELTA5-steroid dehydrogenase adrenal cortex isozyme type 2 656091 1.1.1.149 20alpha-hydroxysteroid dehydrogenase adrenal cortex - -, 668428 1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+) adrenal cortex - 347830 1.1.1.38 malate dehydrogenase (oxaloacetate-decarboxylating) adrenal cortex - 286698 1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+) adrenal cortex - 286980 1.1.1.62 17beta-estradiol 17-dehydrogenase adrenal cortex - 656654 1.14.14.16 steroid 21-monooxygenase adrenal cortex - 285446, 673924, 734302, 735122 1.14.14.18 heme oxygenase (biliverdin-producing) adrenal cortex constitutive expression of HO-2 688006 1.14.14.19 steroid 17alpha-monooxygenase adrenal cortex - 692540, 726923, 727701, 727953 1.14.14.32 17alpha-hydroxyprogesterone deacetylase adrenal cortex - 706819, 728827 1.14.14.32 17alpha-hydroxyprogesterone deacetylase adrenal cortex zona fasciculata, zona reticularis 665842 1.14.15.4 steroid 11beta-monooxygenase adrenal cortex - 285387, 285389, 285390, 285391, 285393, 285394, 285395, 285396, 285398, 285399, 285400, 285401, 285402, 285403, 285404, 285405, 285410, 285411, 673345, 724701 1.14.15.4 steroid 11beta-monooxygenase adrenal cortex capsular portion in zona glomerulosa cells, decapsular in zonae fasciculata and reticularis 285392, 285397 1.14.15.5 corticosterone 18-monooxygenase adrenal cortex - 438757 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving) adrenal cortex - 285412, 285413, 285414, 285415, 285416, 285417, 285418, 285419, 285420, 285421, 285424, 285425, 285426, 285427, 285428, 285429, 285430, 285431, 285432, 285433, 658811, 703418, 703625, 703876, 704039 1.18.1.6 adrenodoxin-NADP+ reductase adrenal cortex - 718572, 718822, 719028, 719386, 719389, 719398, 719475, 719482, 719751, 719752, 719768, 719769 1.4.3.4 monoamine oxidase adrenal cortex of adrenal gland 655721 1.5.1.15 methylenetetrahydrofolate dehydrogenase (NAD+) adrenal cortex - -, 392084, 392085 2.4.1.41 polypeptide N-acetylgalactosaminyltransferase adrenal cortex Northern blot analysis of human tissues 659136 2.7.11.11 cAMP-dependent protein kinase adrenal cortex - 662180 2.7.11.12 cGMP-dependent protein kinase adrenal cortex - 760323 2.8.2.14 bile-salt sulfotransferase adrenal cortex - 676007 2.8.2.15 steroid sulfotransferase adrenal cortex - 645723, 645739 2.8.2.4 estrone sulfotransferase adrenal cortex - 760317 3.1.1.13 sterol esterase adrenal cortex - 133854 3.1.3.16 protein-serine/threonine phosphatase adrenal cortex - 134673 3.1.3.2 acid phosphatase adrenal cortex sinusoidal cells 666100 3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase adrenal cortex PDE2 668987 3.1.4.53 3',5'-cyclic-AMP phosphodiesterase adrenal cortex - 686518 3.1.4.53 3',5'-cyclic-AMP phosphodiesterase adrenal cortex of newborn mice 686518 3.1.4.53 3',5'-cyclic-AMP phosphodiesterase adrenal cortex tumor tissues from patients with isolated micronodular adrenocortical disease and no mutations in the coding PDE8B sequence or any other related genes (PRKAR1A, PDE11A) show downregulated PDE8B expression compared to normal adrenal cortex. PDE8B is a PDE gene linked to isolated micronodular adrenocortical disease. It is a candidate causative gene for other adrenocortical lesions linked to the cAMP signaling pathway and possibly for tumors in other tissues 686518 3.13.2.1 adenosylhomocysteinase adrenal cortex - 137130 3.4.11.7 glutamyl aminopeptidase adrenal cortex - 36025 3.4.21.B26 proprotein convertase 5 adrenal cortex - 673910, 718009 3.4.21.B26 proprotein convertase 5 adrenal cortex richest source of PC5A 675967 3.4.23.5 cathepsin D adrenal cortex - 36935 3.4.23.B24 signal peptide peptidase adrenal cortex - 752819 3.4.24.64 mitochondrial processing peptidase adrenal cortex - 31387 3.4.24.71 endothelin-converting enzyme 1 adrenal cortex - 31470 3.5.1.23 ceramidase adrenal cortex - 720471 4.2.1.11 phosphopyruvate hydratase adrenal cortex - 665841 4.3.1.3 histidine ammonia-lyase adrenal cortex - 34308 4.3.2.9 gamma-glutamylcyclotransferase adrenal cortex moderate expression 720332 4.6.1.2 guanylate cyclase adrenal cortex - 34865 5.3.3.1 steroid DELTA-isomerase adrenal cortex - 721693 6.3.5.4 asparagine synthase (glutamine-hydrolysing) adrenal cortex - 745756