3.4.24.81	ADAM10 endopeptidase	HVEC cell	both ADAM10 and ADAM17 contribute to SDC1 shedding and IL-8 production by HVECs in response to staphylococcal superantigen toxic shock syndrome toxin TSST-1	734189	
3.4.24.86	ADAM 17 endopeptidase	HVEC cell	ADAM17 proteolytic targets, amphiregulin, transforming growth factor (TGF-alpha), syndecan-1 (SDC1), and tumor necrosis factor receptor 1 (TNFR1), are shed from HVECs in response to staphylococcal superantigen toxic shock syndrome toxin TSST-1. ADAM17, but not related ADAM10, is required for amphiregulin, TGF-alpha, and TNFR1 shedding. Both ADAM10 and ADAM17 contribute to SDC1 shedding and IL-8 production by HVECs in response to TSST-1	734189