1.1.1.1 alcohol dehydrogenase aorta the activity of the class I ADH isoenzyme is significantly lower in the wall of aortic aneurysm than in healthy aorta 697802 1.1.1.141 15-hydroxyprostaglandin dehydrogenase (NAD+) aorta - 741244 1.1.1.145 3beta-hydroxy-DELTA5-steroid dehydrogenase aorta abdominal, expression level determination, especially in female aorta with mild atherosclerotic changes 668413 1.1.1.146 11beta-hydroxysteroid dehydrogenase aorta - 701239 1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming) aorta - 286124 1.1.1.21 aldose reductase aorta - 286239, 668380, 711762, 711859 1.1.1.21 aldose reductase aorta vascular smooth muscle cells 669468 1.1.1.315 11-cis-retinol dehydrogenase aorta 26% mRNA expression of Rdh5 compared to liver 690797 1.1.1.B40 11beta-hydroxysteroid dehydrogenase (NAD+) aorta - 701239 1.11.1.12 phospholipid-hydroperoxide glutathione peroxidase aorta transgenic mouse 698045 1.11.1.6 catalase aorta - 655134 1.11.2.2 myeloperoxidase aorta atherosclerotic aorta 697307 1.13.11.33 arachidonate 15-lipoxygenase aorta - -, 684349, 742845 1.13.11.34 arachidonate 5-lipoxygenase aorta expression is not significantly different between diabetic and control rats. Activation of the 5-lipoxygenase previously reported in streptozotocin-induced diabetic rats can be explained by an augmented sensitivity to cysteinyl leukotrienes in the diabetic aorta 660412 1.14.11.2 procollagen-proline 4-dioxygenase aorta - 745084 1.14.11.2 procollagen-proline 4-dioxygenase aorta embryo 439200 1.14.11.2 procollagen-proline 4-dioxygenase aorta rat abdominal aortas -, 745084 1.14.11.4 procollagen-lysine 5-dioxygenase aorta expression only of LH2long 659845 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase aorta of control and hyperglycemic mice 697557 1.14.12.17 nitric oxide dioxygenase aorta endothelial cells 658747 1.14.13.39 nitric-oxide synthase (NADPH) aorta - 745938 1.14.13.39 nitric-oxide synthase (NADPH) aorta thoracic, muscle 685867 1.14.14.18 heme oxygenase (biliverdin-producing) aorta - 688237 1.15.1.1 superoxide dismutase aorta - 685864 1.17.3.2 xanthine oxidase aorta - 688155, 689994 1.17.3.2 xanthine oxidase aorta lower enzyme activity compared to vena cava 684354 1.17.3.2 xanthine oxidase aorta smooth muscle cells 688146 1.17.3.2 xanthine oxidase aorta wall 686890 1.2.1.3 aldehyde dehydrogenase (NAD+) aorta - 711625 1.2.1.5 aldehyde dehydrogenase [NAD(P)+] aorta - 688446 1.2.1.94 farnesal dehydrogenase aorta - 717961 1.2.3.1 aldehyde oxidase aorta - 693075 1.4.3.13 protein-lysine 6-oxidase aorta - 391736, 391737, 391739, 391742, 655021, 659558, 675286, 684802, 695968, 699875, 713462, 724520 1.4.3.13 protein-lysine 6-oxidase aorta co-localization of LOX and LOXL 659751 1.4.3.13 protein-lysine 6-oxidase aorta different spatial and temporal expression of LOX and LOXL1 during growth and aging, expression analysis of LOXL1 and LOX in the aorta during the development, growth, and aging of LOU rats, overview 701156 1.4.3.13 protein-lysine 6-oxidase aorta LOX, LOXL, LOXL3, low expression level of LOXL2 658189 1.4.3.21 primary-amine oxidase aorta - 687449, 688603 1.4.3.5 pyridoxal 5'-phosphate synthase aorta 1.2% of the activity in liver 655483 1.5.1.34 6,7-dihydropteridine reductase aorta - 741864 1.6.2.4 NADPH-hemoprotein reductase aorta - -, 288616 1.6.3.1 NAD(P)H oxidase (H2O2-forming) aorta - 685975, 711166, 711763, 713366 1.6.3.1 NAD(P)H oxidase (H2O2-forming) aorta abdominal aortic endothelial cells 686418 1.6.3.1 NAD(P)H oxidase (H2O2-forming) aorta aortas of transgenic rats harboring the mouse renin transgene exhibit greater NADPH oxidase activity, reactive oxygen species levels, C-reactive protein, tumor necrosis factor-alpha expression, apoptosis, and wall thickness, which are significantly attenuated by in vivo treatment with angiotensin type 1 receptor blockade by valsartan or the superoxide dismutase/catalase mimetic tempol 687049 1.6.3.1 NAD(P)H oxidase (H2O2-forming) aorta aortic ring 684351 1.6.3.1 NAD(P)H oxidase (H2O2-forming) aorta aortic rings 685982 1.6.3.1 NAD(P)H oxidase (H2O2-forming) aorta cultured aortic smooth muscle cell 684269 1.6.3.1 NAD(P)H oxidase (H2O2-forming) aorta Exposure of mouse aortic rings to hypoxia/reoxygenation significantly increases vessel outgrowth, whereas pharmacological inhibition of NADPH oxidase or genetic deletion of the NADPH oxidase subunit, p47phox significantly suppresses these changes. Increases in myocardial serine-threonine kinase Akt and ERK1/2 activation and vascular endothelial growth factor expression are markedly blunted in the subunit p47phox-deficient mouse subjected to myocardial ischemia-reperfusion compared with the wild-type mouse 684345 1.6.3.1 NAD(P)H oxidase (H2O2-forming) aorta hemin treatment increases hemin oxidase-1 expression and activity in aorta and kidney of apolipoprotein E-deficient mice and significantly reduces both NADPH oxidase activity and superoxide generation in situ. Effects are reversed by tin protoporphyrin-IX and are not associated with changes in isoforms Nox2 or Nox4 protein levels. Inhibition of NADPH oxidase activity by hemin in the aorta is mimicked by bilirubin in vitro 687050 1.8.4.12 peptide-methionine (R)-S-oxide reductase aorta - 686598 1.8.4.2 protein-disulfide reductase (glutathione) aorta - 394828 1.8.5.8 eukaryotic sulfide quinone oxidoreductase aorta - 764408 2.1.1.6 catechol O-methyltransferase aorta - 686194 2.1.1.71 phosphatidyl-N-methylethanolamine N-methyltransferase aorta - 485560 2.3.1.149 Platelet-activating factor acetyltransferase aorta immunohistochemistry shows PAF-AH expression in the intima and in the media of the aorta 693520 2.3.1.26 sterol O-acyltransferase aorta - 486688, 486698, 486703 2.3.1.26 sterol O-acyltransferase aorta 41fold induction of activity after 60 days of cholesterol feeding 486683 2.3.1.26 sterol O-acyltransferase aorta atheroschlerotic tissue 486688, 486703 2.3.1.26 sterol O-acyltransferase aorta extremely low activity 486704 2.4.1.131 GDP-Man:Man3GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase aorta intimal layer 638569 2.4.1.255 protein O-GlcNAc transferase aorta - 703977 2.4.1.255 protein O-GlcNAc transferase aorta distribution of OGTase in the aorta is examined by immunofluorescence microscopy 701898 2.4.1.87 N-acetyllactosaminide 3-alpha-galactosyltransferase aorta - 489479 2.4.3.9 lactosylceramide alpha-2,3-sialyltransferase aorta atherosclerotic and normal aorta 705676 2.4.3.9 lactosylceramide alpha-2,3-sialyltransferase aorta atherosclerotic aortic intima 658140 2.4.3.9 lactosylceramide alpha-2,3-sialyltransferase aorta level of GM3 synthase in membrane-fractions isolated from the atherosclerotic intima are higher compared to those in non-dieased arterial tissue 657703 2.5.1.57 N-acylneuraminate-9-phosphate synthase aorta - 637818 2.6.1.42 branched-chain-amino-acid transaminase aorta endothelial cells 640023 2.7.1.127 inositol-trisphosphate 3-kinase aorta smooth muscle 640742, 640743 2.7.1.52 fucokinase aorta - 641674, 661521, 703298 2.7.10.1 receptor protein-tyrosine kinase aorta smooth muscle 660727 2.7.10.2 non-specific protein-tyrosine kinase aorta endothelial cells, PYK2 673110 2.7.11.10 IkappaB kinase aorta - 760461 2.7.11.12 cGMP-dependent protein kinase aorta - 662462, 674575, 704619, 721982, 722222 2.7.11.12 cGMP-dependent protein kinase aorta aortic homogenate, neointima 721982 2.7.11.12 cGMP-dependent protein kinase aorta high expression of isozymes PKG-1alpha and PKG-1beta 660671 2.7.11.12 cGMP-dependent protein kinase aorta smooth muscle 661575 2.7.11.13 protein kinase C aorta - 662054 2.7.11.16 G-protein-coupled receptor kinase aorta - 491168 2.7.11.17 Ca2+/calmodulin-dependent protein kinase aorta - 491257, 491258, 640685, 671227 2.7.11.17 Ca2+/calmodulin-dependent protein kinase aorta smooth muscle 640688 2.7.11.18 myosin-light-chain kinase aorta - 491268, 661664, 687732 2.7.11.18 myosin-light-chain kinase aorta thoracic 640625 2.7.11.31 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase aorta - -, 644987, 693032, 704431 2.7.3.2 creatine kinase aorta - 642371 2.7.7.23 UDP-N-acetylglucosamine diphosphorylase aorta - 643065 2.7.7.30 fucose-1-phosphate guanylyltransferase aorta - 645224 2.7.8.15 UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase aorta - 645351, 645353 2.7.8.27 sphingomyelin synthase aorta - 668729 2.7.8.27 sphingomyelin synthase aorta high expression of SMS1 mRNA 668729 2.8.1.2 3-mercaptopyruvate sulfurtransferase aorta 3MST and cytosolic and mitochondrial cysteine aminotransferases are localized to endothelial cells of the thoracic aorta 704359 2.8.2.15 steroid sulfotransferase aorta aortic smooth muscle cell line CRL-1999 645740 2.8.2.4 estrone sulfotransferase aorta female aortic smooth muscle cell line CRL-1999 cell 645740 2.8.2.8 [heparan sulfate]-glucosamine N-sulfotransferase aorta - -, 762448 3.1.1.13 sterol esterase aorta - 133849 3.1.1.34 lipoprotein lipase aorta aortic endothelial cells 665649 3.1.1.34 lipoprotein lipase aorta highest expression is found in aorta 690660 3.1.1.47 1-alkyl-2-acetylglycerophosphocholine esterase aorta atherogenic aorta 693520 3.1.2.2 palmitoyl-CoA hydrolase aorta - 646158 3.1.2.20 acyl-CoA hydrolase aorta - 646158 3.1.3.1 alkaline phosphatase aorta - 693930 3.1.3.16 protein-serine/threonine phosphatase aorta smooth muscle 134605 3.1.3.4 phosphatidate phosphatase aorta - 665805 3.1.3.53 [myosin-light-chain] phosphatase aorta - 697357, 704517 3.1.3.53 [myosin-light-chain] phosphatase aorta and large capacitance vessels, predominantly expression of 3’-exon-out/leucine-zipper positive MYPT 1 isoform 663585 3.1.3.53 [myosin-light-chain] phosphatase aorta embryonic and adult, smooth muscle, throughout development, exclusive expression of the splice-in myosin-targeting subunit isoform 646360 3.1.3.53 [myosin-light-chain] phosphatase aorta expression of leucine-zipper positive isoform of MYPT 1 predominantes in healthy animal 664610 3.1.3.53 [myosin-light-chain] phosphatase aorta fetal, same MLCP activities in normal and pulmonary hypertensive fetal sheep 646359 3.1.3.53 [myosin-light-chain] phosphatase aorta fragments of the 110 kDa subunit 646358 3.1.4.1 phosphodiesterase I aorta arteries from hypertensive rats, vascular PDE1A, PDE1B, PDE1C, and PDE5 isoforms -, 715153 3.1.4.11 phosphoinositide phospholipase C aorta PLC delta3 and delta4 649088 3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase aorta - 679248 3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase aorta PDE1 670145 3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase aorta PDE10 670145 3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase aorta PDE11 670145 3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase aorta PDE2 670145 3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase aorta PDE3 670145 3.1.4.35 3',5'-cyclic-GMP phosphodiesterase aorta - 711920, 711923 3.1.4.35 3',5'-cyclic-GMP phosphodiesterase aorta PDE5 670145 3.1.4.35 3',5'-cyclic-GMP phosphodiesterase aorta PDE6 670145 3.1.4.35 3',5'-cyclic-GMP phosphodiesterase aorta PDE9 670145 3.1.4.53 3',5'-cyclic-AMP phosphodiesterase aorta - 685021, 750336 3.1.4.53 3',5'-cyclic-AMP phosphodiesterase aorta PDE4 670145 3.1.4.53 3',5'-cyclic-AMP phosphodiesterase aorta PDE7 670145 3.1.4.53 3',5'-cyclic-AMP phosphodiesterase aorta PDE8 670145 3.1.4.53 3',5'-cyclic-AMP phosphodiesterase aorta weak activity 685021 3.1.6.2 steryl-sulfatase aorta abdominal, STS expression levels are higher in the vascular smooth muscle cells obtained from female aortas with mild atherosclerotic changes than in those with severe atherosclerotic changes in male aortas regardless of atherosclerotic changes 645740 3.1.6.2 steryl-sulfatase aorta adult 645797 3.2.1.18 exo-alpha-sialidase aorta aortic smooth muscle 695452 3.3.2.10 soluble epoxide hydrolase aorta - 707303, 708238, 709564, 710821 3.3.2.10 soluble epoxide hydrolase aorta aortic endothelial cell, treatment with angiotensin II results in increased expression of soluble epoxide hydrolase at both the mRNA and protein level 684014 3.3.2.10 soluble epoxide hydrolase aorta aortic intima of both spontaneously hypertensive rats and rats infused with angiotensin II exhibits an elevated level of soluble epoxide hydrolase 684014 3.3.2.6 leukotriene-A4 hydrolase aorta aortic lesion 684001 3.3.2.7 hepoxilin-epoxide hydrolase aorta - 647027 3.4.11.2 membrane alanyl aminopeptidase aorta endothelial cell 664320, 664501 3.4.13.18 cytosol nonspecific dipeptidase aorta normal and from patients with aortic aneurysms 137197 3.4.13.9 Xaa-Pro dipeptidase aorta enzyme activity is increased in aortic dilatation compared to controls 710614 3.4.14.2 dipeptidyl-peptidase II aorta - 651779 3.4.15.1 peptidyl-dipeptidase A aorta - 670113, 699781, 707783, 709124, 709149, 709653, 731569 3.4.15.1 peptidyl-dipeptidase A aorta the direct antioxidative and anti-inflammatory effects of peroxisome proliferator-activated receptors ligands are associated with the inhibition of angiotensin converting enzyme expression in streptozotocin-induced diabetic rat aorta 679664 3.4.16.2 lysosomal Pro-Xaa carboxypeptidase aorta aortic aneurysm and normal aorta 36275 3.4.17.23 angiotensin-converting enzyme 2 aorta - 762703 3.4.19.12 ubiquitinyl hydrolase 1 aorta vascular smooth muscle cells. UCH-L1 is up-regulated in injured arteries 707391 3.4.21.37 leukocyte elastase aorta aortic endothelial cells 707071 3.4.21.37 leukocyte elastase aorta aortic smooth muscle cells 707071 3.4.21.39 chymase aorta - 699756 3.4.21.B26 proprotein convertase 5 aorta - 718009 3.4.21.B26 proprotein convertase 5 aorta PC5A dominates 675967 3.4.21.B5 mast cell protease 5 aorta - 699756 3.4.22.15 cathepsin L aorta increased level of cathepsin L in atherosclerotic lesions compared with healthy aortas 695435 3.4.22.27 cathepsin S aorta smooth muscle cells 667140 3.4.22.34 Legumain aorta lesions at the aortic sinus and in injured carotid arteries of Apolipoprotein E deficient mice, mRNA expression increases with development of atherosclerosis in the aorta 683113 3.4.22.38 cathepsin K aorta in the macrophage-rich regions of atherosclerotic plaques 708148 3.4.22.43 cathepsin V aorta expression in aorta valve, control valves and stenotic valves analyzed 683107 3.4.22.52 calpain-1 aorta - 708018 3.4.22.53 calpain-2 aorta - 708151 3.4.22.53 calpain-2 aorta relatively high m-calpain expression levels in the inferior arch 708018 3.4.22.B29 calpain 9 aorta - 664555 3.4.23.5 cathepsin D aorta - 36921 3.4.24.11 neprilysin aorta tissue NEP activity and its protein and mRNA expression are lower in the late phase of the septic shock compared to the early phase of the shock and the control 670860 3.4.24.14 procollagen N-endopeptidase aorta - 754590 3.4.24.15 thimet oligopeptidase aorta aortic endothelial cell culture. Enzyme is sensitive to Gialpha2/3 inhibition. Under cyclic strain conditions, level of secreted enzyme increases 2.6fold 667354 3.4.24.24 gelatinase A aorta - 754999 3.4.24.34 neutrophil collagenase aorta matrix metalloproteinase-8 is increased at the site of abdominal aortic aneurysm rupture 683357 3.4.24.34 neutrophil collagenase aorta MMP-8 is localized to mesenchymal cells within the adventitia of the aortic wall 668115 3.4.24.35 gelatinase B aorta - 697149, 699878 3.4.24.71 endothelin-converting enzyme 1 aorta - 683318 3.4.24.71 endothelin-converting enzyme 1 aorta determination of enzyme expression by immunohistochemical analysis on atherosclerotic and nonatherosclerotic vascular tissue using a combination of ECE-1 isoform-specific antibodies, distinct expression patterns for ECE-1a and ECE-1c, overview 683440 3.4.24.71 endothelin-converting enzyme 1 aorta increased ECE-1 protein content (immunohistochemistry, immunoblot) and mRNA expression (Northern blot) in apolipoprotein E-deficient mouse -, 699415 3.4.24.80 membrane-type matrix metalloproteinase-1 aorta aortic fibroblasts 754508 3.4.24.81 ADAM10 endopeptidase aorta - 755575 3.4.24.82 ADAMTS-4 endopeptidase aorta - 755457 3.4.24.82 ADAMTS-4 endopeptidase aorta low expression in non-atherosclerotic aorta 677894 3.4.24.86 ADAM 17 endopeptidase aorta - 753291 3.4.24.86 ADAM 17 endopeptidase aorta atherosclerotic lesions of apolipoprotein E-deficient mice 667364 3.4.24.86 ADAM 17 endopeptidase aorta intraluminal thrombus of human abdominal aortic aneurysm 755575 3.4.24.86 ADAM 17 endopeptidase aorta metalloproteases ADAM-9, ADAM-15, and ADAM-17 are upregulated in advanced human atherosclerotic lesions in samples from carotid, abdominal aortic, and femoral territories compared to samples from internal thoracic artery free of atherosclerotic plaques. ADAM-9, ADAM-15, and ADAM-17-expressing cells colocalize with CD68-positive cells of monocytic origin in the atherosclerotic plaques 710868 3.4.24.B11 ADAMTS1 endopeptidase aorta - 755146 3.4.24.B12 ADAMTS5 endopeptidase aorta - 734180 3.4.24.B4 matrix metalloproteinase-13 aorta healthy and elastase-perfused aortas. Increased MMP-13 in experimental abdominal aortic aneurysms in males compared with females, while there are no differences in aortic diameter, collagen, and MMP-13 levels in baseline males versus females, MMP-13 expression analysis, overview 713523 3.4.24.B9 ADAM9 endopeptidase aorta - 710868 3.5.3.1 arginase aorta - 688758 3.5.3.1 arginase aorta intact aorta 670422 3.5.3.18 dimethylargininase aorta - 288970, 668120, 695485, 698209 3.5.4.16 GTP cyclohydrolase I aorta - 698049, 698205, 698211 3.5.4.9 methenyltetrahydrofolate cyclohydrolase aorta - 757773 3.6.1.13 ADP-ribose diphosphatase aorta - 209946 3.6.1.5 apyrase aorta - 210132, 210162 3.6.1.5 apyrase aorta aortic endothelial cells 210150 3.6.1.5 apyrase aorta intima and media layers 210168 3.6.1.5 apyrase aorta smooth muscle cells 210167 3.6.1.6 nucleoside diphosphate phosphatase aorta - -, 719196 4.1.1.17 ornithine decarboxylase aorta - 695461 4.1.1.19 arginine decarboxylase aorta highest activity of all tissues tested 656583 4.1.1.22 histidine decarboxylase aorta - 665184 4.2.1.92 hydroperoxide dehydratase aorta - 684349 4.4.1.1 cystathionine gamma-lyase aorta - 690352, 692207, 695134, 707582, 746708 4.4.1.5 lactoylglutathione lyase aorta - 37413, 729179 4.4.1.5 lactoylglutathione lyase aorta aortic sinus derived from apolipoprotein-E-knockout mouse on a high-fat diet for 6 months, enzyme expression is restricted to a subset of cells 729179 4.6.1.1 adenylate cyclase aorta - 690360 4.6.1.2 guanylate cyclase aorta - 691542, 691656, 693256, 693826 4.6.1.2 guanylate cyclase aorta aortic ring 693812 4.6.1.2 guanylate cyclase aorta human aortic smooth muscle cells 693087 4.6.1.2 guanylate cyclase aorta primary aortic smooth muscle cells 691841 4.6.1.2 guanylate cyclase aorta vascular wall and smooth muscle cells 691659 5.3.99.4 prostaglandin-I synthase aorta - 3200, 37458, 37460, 37461, 37462, 37463, 37465, 37466, 37467, 37468, 37469, 37470, 37475, 37476, 37477, 37478, 37479, 37480, 37485, 660924, 681029 5.3.99.4 prostaglandin-I synthase aorta atherosclerotic aorta 701992 5.3.99.4 prostaglandin-I synthase aorta normal aortic endothelium. Co-distribution of prostaglandin cyclase and cyclooxygenase COX-1, while expression of cyclooxygenase COX-2 is not detected in endothelium 678436 5.3.99.4 prostaglandin-I synthase aorta normal aortic endothelium. Co-distribution of prostaglandin cyclase and cyclooxygenase COX-1, with only minor expression of cyclooxygenase COX-2 in endothelium 678436 5.3.99.4 prostaglandin-I synthase aorta normal aortic endothelium. Prostaglandin cyclase, cyclooxygenase COX-1 and thromboxane synthase are widely distributed throughout the endothelium. There is greater co-distribution of prostacyclin synthase with isoform COX-1 compared to isoform COX-2 678436 5.3.99.4 prostaglandin-I synthase aorta significant suppression of enzyme activity in parallel with increased superoxide and enzyme nitration in the aortas of diabetic C57BL6 mice, but less effect in diabetic mice either lacking endothelial nitric oxide synthase or overexpressing human superoxide dismutase 679435 5.3.99.5 thromboxane-A synthase aorta atherosclerotic aorta 701992 5.3.99.5 thromboxane-A synthase aorta thromboxane synthase, prostaglandin cyclase and cyclooxygenase COX-1 are widely distributed throughout normal aortic endothelium 678436 5.3.99.5 thromboxane-A synthase aorta TXAS is expressed in the atherosclerotic lesion, associated with increased inflammatory cells, in particular M2 polarized macrophages 705219 5.6.1.6 channel-conductance-controlling ATPase aorta - 675622 6.2.1.3 long-chain-fatty-acid-CoA ligase aorta highly expressed in vascular endothelium 650399 6.3.4.5 argininosuccinate synthase aorta - 690727, 690765 6.3.4.5 argininosuccinate synthase aorta endothelial cell 662377 7.2.2.13 Na+/K+-exchanging ATPase aorta - 246966, 735119 7.2.2.13 Na+/K+-exchanging ATPase aorta electrogenic Na+K+-ATPase partially contributes to the ustained hyperpolarization of endothelial cells in response to acetylcholine 685863 7.2.2.8 P-type Cu+ transporter aorta - -, 733703, 749535 7.2.2.9 P-type Cu2+ transporter aorta - 668543 7.6.2.1 P-type phospholipid transporter aorta epithelial cells 246839