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BTO (BRENDA Tissue Ontology)
Download as: OBO OWL
Version 2021-10-23
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Details for A3 cell
A3 cell
BTO (BRENDA Tissue Ontology) ID
BTO:0001342
BTO:0001342 is linked to 2 enzymes:
Definition
Human T lymphocyte, acute T cell leukemia cell line. Morphology: lymphoblastoid. The A3 subclone was derived from a Jurkat cell line obtained from the laboratory of Gerald Crabtree at Stanford University. The Jurkat cells were treated with Fas Antibody and isolated by limiting dilution to obtain a cell line that had a low spontaneous rate of resistance to Fas-medicated apoptosis. The resulting wild-type A3 subclone is very sensitive to Fas-mediated apoptosis
Synonyms
1. Jurkat A3 cell
2. Jurkat clone A3 cell
References
1. ATCC American Cell Type Culture Collection: http://www.lgcstandards-atcc.org/
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