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Gene ontology
Version 2014-12-22
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Details for UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
6.3.2.10
Gene ontology ID
GO:0047480
Definition
Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP + D-alanyl-D-alanine = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP
Comment
Note that the enzyme UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase also has UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity (GO:0008766).
Synonyms
1. MurF synthetase activity
2. UDP-MurNAc-L-Ala-D-Glu-L-Lys:D-Ala-D-Ala ligase activity
3. UDP-MurNAc-pentapeptide synthetase activity
4. UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine:D-alanyl-D-alanine ligase (ADP-forming)
5. UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine synthetase activity
6. UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine synthetase activity
7. UDP-N-acetylmuramoylalanine-D-glutamyl-lysine--D-alanyl-D-alanine ligase activity
8. UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity
9. UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase activity
10. UDP-N-acetylmuramoylalanyl-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity
11. UDP-N-acetylmuramoylalanyl-tripeptide-D-alanyl-D-alanine ligase activity
12. UDPacetylmuramoylpentapeptide synthetase activity
13. uridine diphosphoacetylmuramoylpentapeptide synthetase activity
References
1. EC 6.3.2.10
2. MetaCyc 6.3.2.10-RXN
3. RHEA: 16085
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