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Gene ontology
Version 2014-12-22
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Details for 1-phosphatidylinositol-5-phosphate 4-kinase activity
2.7.1.149
Gene ontology ID
GO:0016309
Definition
Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
Synonyms
1. 1-phosphatidylinositol-5-phosphate kinase
2. ATP:1-phosphatidyl-1D-myo-inositol-5-phosphate 4-phosphotransferase activity
3. PIP4K
4. type II PIP kinase activity
References
1. EC 2.7.1.149
2. MetaCyc 2.7.1.149-RXN
3. Reactome: R-HSA-1675776 "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane"
4. Reactome: R-HSA-6811522 "PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus"
5. RHEA: 12280
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