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Gene ontology
Version 2014-12-22
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Details for glycoprotein 6-alpha-L-fucosyltransferase activity
2.4.1.68
Gene ontology ID
GO:0008424
Definition
Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->6)]-N-acetyl-beta-D-glucosaminyl}asparagine + GDP + H(+)
Synonyms
1. FucT
2. GDP-fucose--glycoprotein fucosyltransferase activity
3. GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1,6)fucosyltransferase activity
4. GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1->6)fucosyltransferase activity
5. GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1,6)fucosyltransferase activity
6. GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1->6)fucosyltransferase activity
7. GDP-L-fucose--glycoprotein fucosyltransferase activity
8. GDPfucose-glycoprotein fucosyltransferase activity
9. glycoprotein fucosyltransferase activity
10. guanosine diphosphofucose--glycoprotein fucosyltransferase activity
References
1. EC 2.4.1.68
2. RHEA: 12985
3. KEGG REACTION: R05988
4. MetaCyc 2.4.1.68-RXN
5. Reactome: R-HSA-1028788 "FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP"
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