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Gene ontology
Version 2014-12-22
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Details for sterol 14-demethylase activity
1.14.13.70
Gene ontology ID
GO:0008398
Definition
Catalysis of the reaction: obtusifoliol + 3 O2 + 3 NADPH + 3 H+ = 4-alpha-methyl-5-alpha-ergosta-8,14,24(28)-trien-3-beta-ol + formate + 3 NADP+ + 3 H2O
Synonyms
1. cytochrome P450 51 activity
2. cytochrome P450 CYP51
3. lanosterol 14-alpha-demethylase activity
4. lanosterol 14-demethylase activity
5. lanosterol 14alpha-demethylase activity
6. obtusufoliol 14-demethylase activity
7. sterol 14-alpha-demethylase activity
8. sterol 14alpha-demethylase activity
9. sterol,NADPH:oxygen oxidoreductase (14-methyl cleaving)
References
1. EC 1.14.13.70
2. MetaCyc 1.14.13.70-RXN
3. Reactome: R-HSA-194678 "CYP51A1 demethylates LNSOL"
4. RHEA: 14917
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Gene ontology