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Gene ontology
Version 2014-12-22
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Details for protein farnesyltransferase activity
2.5.1.58
Gene ontology ID
GO:0004660
Definition
Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate
Comment
The catalyzed reaction transfers a farnesyl group from farnesyl diphosphate to a target protein. There is no relationship between this activity and farnesyltransferase activity, GO:0004311, where the catalyzed reaction forms (free) geranylgeranyl diphosphate.
Synonyms
1. CAAX farnesyltransferase activity
2. farnesyl-diphosphate:protein-cysteine farnesyltransferase activity
3. FTase activity
4. protein-cysteine farnesyltransferase activity
References
1. EC 2.5.1.58
2. PMID 8621375
3. MetaCyc 2.5.1.58-RXN
4. Reactome: R-HSA-2530501 "FNTA:FNTB transfers FARN to GNGT1"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
molecular_function is a
catalytic activity is a
catalytic activity, acting on a protein is a
protein prenyltransferase activity is a
protein farnesyltransferase activity is a
Tree view
Gene ontology
biological_process is a
cellular_component is a
molecular_function is a
binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
alpha-1,4-glucan-protein synthase (ADP-forming) activity is a
biotin-protein ligase activity is a
catalytic activity, acting on a glycoprotein is a
deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase activity is a
dihydrolipoyllysine-residue acetyltransferase activity is a
dihydrolipoyllysine-residue succinyltransferase activity is a
GPI-anchor transamidase activity is a
lipoate-protein ligase activity is a
peptidyl-aspartic acid 3-dioxygenase activity is a
peptidyl-lysine N6-palmitoyltransferase activity is a
peptidylamidoglycolate lyase activity is a
phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity is a
polypeptide N-acetylgalactosaminyltransferase activity is a
procollagen galactosyltransferase activity is a
procollagen glucosyltransferase activity is a
protein disulfide isomerase activity is a
protein methylesterase activity is a
protein methylthiotransferase activity is a
protein N-acetylglucosaminyltransferase activity is a
protein O-GlcNAc transferase activity is a
protein prenyltransferase activity is a
protein farnesyltransferase activity is a
protein geranylgeranyltransferase activity is a
protein xylosyltransferase activity is a
protein-cysteine S-acyltransferase activity is a
protein-fructosamine 3-kinase activity is a
protein-glucosylgalactosylhydroxylysine glucosidase activity is a
protein-glutamic acid ligase activity is a
protein-glycine ligase activity is a
protein-ribulosamine 3-kinase activity is a
protein-tyrosine sulfotransferase activity is a
Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity is a
transferase activity, transferring amino-acyl groups is a
tubulin-tyrosine ligase activity is a
ubiquitin-like protein transferase activity is a
ubiquitinyl hydrolase activity is a
[acyl-carrier-protein] phosphodiesterase activity is a
[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase is a
[protein-PII] uridylyltransferase activity is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
isomerase activity is a
ligase activity is a
lyase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a