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Gene ontology
Version 2014-12-22
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Details for N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity
2.4.1.141
Gene ontology ID
GO:0004577
Definition
Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP + N,N''-diacetylchitobiosyldiphosphodolichol
Synonyms
1. N,N'-diacetylchitobiosylpyrophosphoryldolichol synthase activity
2. UDP-GlcNAc:dolichyl-pyrophosphoryl-GlcNAc GlcNAc transferase activity
3. UDP-N-acetyl-D-glucosamine:N-acetyl-D-glucosaminyl-diphosphodolichol N-acetyl-D-glucosaminyltransferase activity
4. uridine diphosphoacetylglucosamine-dolichylacetylglucosamine pyrophosphate acetylglucosaminyltransferase activity
References
1. EC 2.4.1.141
2. MetaCyc 2.4.1.141-RXN
3. Reactome: R-HSA-446207 "ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP"
4. Reactome: R-HSA-5633241 "Defective ALG14 does not transfer GlcNAc from UDP-GlcNAc to GlcNAcDOLP"
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