1.14.16.1Gene ontology ID
GO:0004505
Definition
Catalysis of the reaction: L-phenylalanine + tetrahydrobiopterin + O2 = L-tyrosine + 4-alpha-hydroxytetrahydrobiopterin
Synonyms
1. L-phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)
2. PAH activity
3. phenylalaninase activity
4. phenylalanine 4-hydroxylase activity
5. phenylalanine hydroxylase activity
References
1. EC 1.14.16.12. MetaCyc PHENYLALANINE-4-MONOOXYGENASE-RXN3. Reactome: R-HSA-5649483 "Defective PAH does not hydroxylate L-Phe to L-Tyr"
4. Reactome: R-HSA-71118 "PAH tetramer hydroxylates L-Phe to L-Tyr"
5. RHEA: 20273
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
/
/
at least 1 tissue/ enzyme/ localization link in this branch
/
/
tissue/ enzyme/ localization link to BRENDA