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Gene ontology
Version 2014-12-22
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Details for mRNA guanylyltransferase activity
2.7.7.50
Gene ontology ID
GO:0004484
Definition
Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue
Synonyms
1. GTP--RNA guanylyltransferase activity
2. GTP:mRNA guanylyltransferase activity
3. messenger RNA guanylyltransferase activity
4. mRNA capping enzyme activity
5. protein lambda2
References
1. EC 2.7.7.50
2. MetaCyc MRNA-GUANYLYLTRANSFERASE-RXN
3. Reactome: R-HSA-77081 "Formation of the CE:GMP intermediate complex"
4. Reactome: R-HSA-77083 "Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA"
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