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Gene ontology
Version 2014-12-22
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Details for GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity
2.4.1.132
Gene ontology ID
GO:0004378
Definition
Catalysis of the reaction: beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose = alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP + H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->3)-D-mannosyl-D-mannose linkage
Synonyms
1. GDP-D-mannose:D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol 3-alpha-mannosyltransferase activity
2. GDP-mannose-oligosaccharide-lipid mannosyltransferase II
3. GDP-mannose:glycolipid 1,3-alpha-D-mannosyltransferase activity
4. glycolipid 3-alpha-mannosyltransferase activity
5. guanosine diphosphomannose-oligosaccharide-lipid II mannosyltransferase activity
6. mannosyltransferase II activity
References
1. EC 2.4.1.132
2. MetaCyc 2.4.1.132-RXN
3. RHEA: 29515
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