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Gene ontology
Version 2014-12-22
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Details for ATP citrate synthase activity
2.3.3.8
Gene ontology ID
GO:0003878
Definition
Catalysis of the reaction: acetyl-CoA + ADP + H(+) + oxaloacetate + phosphate = ATP + citrate + CoA
Comment
Note that this function was formerly EC:4.1.3.8.
Synonyms
1. acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity
2. acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)
3. acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]
4. adenosine triphosphate citrate lyase activity
5. ATP citrate (pro-S)-lyase activity
6. ATP-citrate (pro-S)-lyase activity
7. ATP-citrate (pro-S-)-lyase activity
8. ATP-citric lyase activity
9. ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity
10. ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)
11. citrate cleavage enzyme activity
12. citrate-ATP lyase activity
13. citric cleavage enzyme activity
References
1. EC 2.3.3.8
2. RHEA: 21160
3. KEGG REACTION: R00352
4. MetaCyc ATP-CITRATE-PRO-S--LYASE-RXN
5. MetaCyc PWY-5172
6. Reactome: R-HSA-75848 "ACLY tetramer transforms CIT to Ac-CoA"
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derives from the parent element
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