EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
6.3.1.2 | alpha-ketoglutarate | activates | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
6.3.1.2 | Ala | - |
Rattus norvegicus | |
6.3.1.2 | Carbamoyl phosphate | - |
Rattus norvegicus | |
6.3.1.2 | Gly | - |
Rattus norvegicus | |
6.3.1.2 | L-methionine sulfoximine | - |
Rattus norvegicus | |
6.3.1.2 | L-methionine sulfoximine | - |
Sus scrofa | |
6.3.1.2 | Ser | - |
Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
6.3.1.2 | 0.18 | - |
NH4+ | Mg2+-stimulated | Ovis aries | |
6.3.1.2 | 2.3 | - |
ATP | ATP, Mg2+-stimulated | Ovis aries | |
6.3.1.2 | 2.5 | - |
ATP | L-Glu, Mg2+-stimulated | Rattus norvegicus |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
6.3.1.2 | Co2+ | at pH 7.2, Mg2+ is more effective than Co2+ | Rattus norvegicus | |
6.3.1.2 | Mg2+ | - |
Sus scrofa | |
6.3.1.2 | Mg2+ | at pH 7.2, Mg2+ is more effective than Mn2+ | Rattus norvegicus | |
6.3.1.2 | Mn2+ | at pH 7.2, Mg2+ is more effective than Mn2+ | Rattus norvegicus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
6.3.1.2 | 44000 | - |
x * 44000, SDS-PAGE | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.3.1.2 | Cricetulus griseus | - |
- |
- |
6.3.1.2 | Gallus gallus | - |
- |
- |
6.3.1.2 | Homo sapiens | - |
- |
- |
6.3.1.2 | Mammalia | - |
- |
- |
6.3.1.2 | Ovis aries | - |
- |
- |
6.3.1.2 | Rattus norvegicus | - |
- |
- |
6.3.1.2 | Sus scrofa | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
6.3.1.2 | brain | - |
Homo sapiens | - |
6.3.1.2 | brain | - |
Rattus norvegicus | - |
6.3.1.2 | brain | - |
Sus scrofa | - |
6.3.1.2 | brain | - |
Ovis aries | - |
6.3.1.2 | liver | - |
Gallus gallus | - |
6.3.1.2 | liver | - |
Cricetulus griseus | - |
6.3.1.2 | liver | - |
Homo sapiens | - |
6.3.1.2 | liver | - |
Rattus norvegicus | - |
6.3.1.2 | neural retina | - |
Gallus gallus | - |
6.3.1.2 | spleen | - |
Rattus norvegicus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
6.3.1.2 | 8.93 | - |
- |
Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.3.1.2 | ATP + L-Glu + NH4+ | - |
Gallus gallus | ADP + phosphate + L-Gln | - |
? | |
6.3.1.2 | ATP + L-Glu + NH4+ | - |
Cricetulus griseus | ADP + phosphate + L-Gln | - |
? | |
6.3.1.2 | ATP + L-Glu + NH4+ | - |
Mammalia | ADP + phosphate + L-Gln | - |
? | |
6.3.1.2 | ATP + L-Glu + NH4+ | - |
Homo sapiens | ADP + phosphate + L-Gln | - |
? | |
6.3.1.2 | ATP + L-Glu + NH4+ | - |
Sus scrofa | ADP + phosphate + L-Gln | - |
? | |
6.3.1.2 | ATP + L-Glu + NH4+ | enzyme can bind 8 M of ATP per mol of enzyme | Ovis aries | ADP + phosphate + L-Gln | - |
? | |
6.3.1.2 | ATP + L-Glu + NH4+ | 1 mol of enzyme can bind 5 M ATP | Rattus norvegicus | ADP + phosphate + L-Gln | - |
? | |
6.3.1.2 | Gln + hydroxylamine + ADP | - |
Gallus gallus | gamma-Glutamylhydroxamate + NH4+ + ? | - |
? | |
6.3.1.2 | Gln + hydroxylamine + ADP | - |
Cricetulus griseus | gamma-Glutamylhydroxamate + NH4+ + ? | - |
? | |
6.3.1.2 | Gln + hydroxylamine + ADP | - |
Homo sapiens | gamma-Glutamylhydroxamate + NH4+ + ? | - |
? | |
6.3.1.2 | Gln + hydroxylamine + ADP | - |
Rattus norvegicus | gamma-Glutamylhydroxamate + NH4+ + ? | - |
? | |
6.3.1.2 | Gln + hydroxylamine + ADP | - |
Sus scrofa | gamma-Glutamylhydroxamate + NH4+ + ? | - |
? | |
6.3.1.2 | Gln + hydroxylamine + ADP | - |
Ovis aries | gamma-Glutamylhydroxamate + NH4+ + ? | - |
? | |
6.3.1.2 | Gln + hydroxylamine + ADP | ADP or ATP required | Mammalia | gamma-Glutamylhydroxamate + NH4+ + ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
6.3.1.2 | ? | x * 44000, SDS-PAGE | Rattus norvegicus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
6.3.1.2 | additional information | - |
optimum varies from about pH 4.8 to 8.5 depending upon the nature and concentration of the divalent cation present | Rattus norvegicus |