Any feedback?
Literature summary for 6.5.1.1 extracted from
- Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair (2011), Nature, 471, 245-248.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Mus musculus | 5739 | - |
| nucleus | - |
Mus musculus | 5634 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | Lig3 contains a zinc finger | Mus musculus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| embryonic stem cell | - |
Mus musculus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ATP-dependent DNA ligase | - |
Mus musculus |
| DNA ligase III | - |
Mus musculus |
| Lig3 | - |
Mus musculus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Mus musculus | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | loss of Lig3 is not associated with sensitivity to several DNA-damaging agents or with increased sister-chromatid exchange | Mus musculus |
| physiological function | the mitochondrial, but not nuclear, Lig3 is required for cellular viability | Mus musculus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
