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Literature summary for 6.5.1.1 extracted from

  • Kusumoto, R.; Dawut, L.; Marchetti, C.; Wan Lee, J.; Vindigni, A.; Ramsden, D.; Bohr, V.A.
    Werner protein cooperates with the XRCC4-DNA ligase IV complex in end-processing (2008), Biochemistry, 47, 7548-7556.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information Werner protein physically interacts with X4L4 which stimulates Werner protein exonuclease but not its helicase activity, human RecQ helicase BLM protein which possesses only helicase activity, does not bind to X4L4, and its helicase activity is not affected by X4L4 Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
X4L4
-
Homo sapiens
XRCC4-DNA ligase IV complex the X4L4 complex contains two subunits of XRCC4 and one subunit of ligase IV Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
Homo sapiens