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Literature summary for 6.3.5.7 extracted from

  • Nagao, A.; Suzuki, T.; Katoh, T.; Sakaguchi, Y.; Suzuki, T.
    Biogenesis of glutaminyl-mt tRNAGln in human mitochondria (2009), Proc. Natl. Acad. Sci. USA, 106, 16209-16214.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 6.3.5.7

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Homo sapiens 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
132000
-
 gel filtration, GatABC complex Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens O43716 subunit C
-
Homo sapiens O75879 subunit B
-
Homo sapiens Q9H0R6 subunit A
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + Glu-tRNAGln + L-glutamine
-
 Homo sapiens ADP + phosphate + Gln-tRNAGln + L-glutamate
-
 ?

Subunits

Subunits Comment Organism
trimer 1 * subunit A plus 1 * subunit B plus 1 * subunit C Homo sapiens

General Information

General Information Comment Organism
physiological function inactivation of any of the hGatCAB subunits by siRNA-mediated knock down in HeLa cells leads to accumulation of the Glu-charged form of tRNAGln and defects in respiration can be observed Homo sapiens