Activating Compound | Comment | Organism | Structure |
---|---|---|---|
N-acetyl-L-glutamate | only CPS III | Clarias batrachus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
UMP | only CPS II | Clarias batrachus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.46 | - |
L-glutamine | pH 7.5, 30°C | Clarias batrachus | |
2.2 | - |
ammonia | pH 7.5, 30°C | Clarias batrachus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | CPS II | Clarias batrachus | 5829 | - |
mitochondrion | CPS III | Clarias batrachus | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 ATP + L-Gln + HCO3- | Clarias batrachus | enzyme is a key enzyme in the pyrimidine nucleotide and arginine biosynthetic pathways | 2 ADP + phosphate + L-Glu + carbamoyl phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Clarias batrachus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
recombinant wild-type and mutant enzymes | Clarias batrachus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 ATP + L-Gln + HCO3- | - |
Clarias batrachus | 2 ADP + phosphate + L-Glu + carbamoyl phosphate | - |
? | |
2 ATP + L-Gln + HCO3- | enzyme is a key enzyme in the pyrimidine nucleotide and arginine biosynthetic pathways | Clarias batrachus | 2 ADP + phosphate + L-Glu + carbamoyl phosphate | - |
? | |
2 ATP + NH4+ + HCO3- | - |
Clarias batrachus | 2 ADP + phosphate + carbamoyl phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CPS II (glutamine-dependent) | - |
Clarias batrachus |
CPS III (glutamine- and N-acetyl-L-glutamine-dependent) | - |
Clarias batrachus |