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Literature summary for 6.3.5.5 extracted from

  • Mori, M.; Tatibana, M.
    Glutamine-dependent carbamoyl phosphate synthetase: polyamines inhibit the activity and modify the activating effect of 5-phosphoribosyl 1-pyrophosphate (1975), Biochem. Biophys. Res. Commun., 67, 287-293.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
polyamines inhibition is partially reversed by increasing the concentration of Mg2+ or MgATP2-, or by adding low concentrations of 5-phosphoribosyl 1-diphosphate Mammalia
polyamines
-
Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Mammalia
-
-
-
Mus musculus
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-
spleen
-
Mus musculus
-
spleen
-
Rattus norvegicus
-
Yoshida AH-130 cell
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 ATP + L-Gln + HCO3-
-
Mammalia 2 ADP + phosphate + L-Glu + carbamoyl phosphate
-
?
2 ATP + L-Gln + HCO3-
-
Mus musculus 2 ADP + phosphate + L-Glu + carbamoyl phosphate
-
?
2 ATP + L-Gln + HCO3-
-
Rattus norvegicus 2 ADP + phosphate + L-Glu + carbamoyl phosphate
-
?