Protein Variants | Comment | Organism |
---|---|---|
R143L | although the mutants R143L and D13A have low or no activity independently, when they are mixed, a significant amount of activity is obtained. These results indicate that the subunits exchange with each other to form heterodimers with a single viable active site | Escherichia coli |
General Stability | Organism |
---|---|
GTP and IMP stabilize the dimeric structure | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
wild-type and mutant enzymes R143L and D13A | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + IMP + L-Asp | - |
Escherichia coli | GDP + phosphate + adenylosuccinate | - |
? |