Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 6.3.4.4 extracted from

  • Poland, B.W.; Lee, S.F.; Subramanian, M.V.; Siehl, D.L.; Anderson, R.J.; Fromm, H.J.; Honzatko, R.B.
    Refined crystal structure of adenylsuccinate synthetase from Escherichia coli complexed with hydantocidin 5'-phosphate, GDP, HPO42-, Mg2+, and hadacidin (1996), Biochemistry, 35, 15753-15759.
    View publication on PubMed
Search for more literature for 6.3.4.4

Crystallization (Commentary)

Crystallization (Comment) Organism
crystal structure of the enzyme complexed with GDP, IMP hadacidin, NO3-, and Mg2+ Escherichia coli

Inhibitors

Inhibitors Comment Organism Structure
GDP
-
 Escherichia coli
Hadacidin
-
 Escherichia coli
IMP
-
 Escherichia coli
additional information hydantocidin 5'-phosphate, GDP, HPO42-, and Mg2+ may represent a set of synergistic inhibitors even more effective than the combination of IMP, GDP, NO3-, and Mg2+ Escherichia coli
NO3-
-
 Escherichia coli

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0596
-
 IMP wild-type Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli P0A7D4
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + IMP + L-Asp
-
 Escherichia coli GDP + phosphate + adenylosuccinate
-
 ?