Organism | UniProt | Comment | Textmining |
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Crenarchaeota | - |
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Synonyms | Comment | Organism |
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queC | - |
Crenarchaeota |
General Information | Comment | Organism |
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evolution | the enzyme belongs to GAT-QueC, a two-domain family with an N-terminal glutamine amidotransferase class-II domain fused to a domain homologous to QueC, the enzyme that produces preQ0. Phylogenetic distribution of aTGT, ArcS, GAT-QueC, and QueF-like in the two archaeal phyla, overview. Most crenarchaeal genomes encode a fused GAT-QueC protein or a QueF-like protein | Crenarchaeota |
physiological function | the enzyme QueC produces the G+ precursor, 7-cyano-7-deazaguanine, i.e. preQ0, which is inserted into tRNA by tRNA-guanine transglycosylase before conversion into G+ by archaeosine synthase, ArcS. Gat-QueC and QueF-like families can compensate for lack of ArcS, overview | Crenarchaeota |