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Literature summary for 6.3.4.15 extracted from

  • Streaker, E.D.; Beckett, D.
    The biotin regulatory system: kinetic control of a transcriptional switch (2006), Biochemistry, 45, 6417-6425.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + biotin + apo-[acetyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
Escherichia coli AMP + diphosphate + [acetyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
?

Subunits

Subunits Comment Organism
dimer
-
Escherichia coli

Synonyms

Synonyms Comment Organism
biotin protein ligase
-
Escherichia coli
BirA bifunctional protein, catalyzes post-translational biotin addition to a biotin-dependent carboxylase and binds sequence-specifically to DNA to repress transcription initiation at the biotin biosynthetic operon Escherichia coli

Cofactor

Cofactor Comment Organism Structure
ATP
-
Escherichia coli