Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-amino-N,N-dibenzyl-1,3-oxazole-5-carboxamide | minimal inhibitory concentration above 64 microg per ml for wild-type, 16 microg per ml for mutant with targeted knock-out of efflux pump tolC and imp gene disruption | Escherichia coli | |
2-amino-N,N-dibenzyl-1,3-oxazole-5-carboxamide | minimal inhibitory concentration above 64 microg per ml for wild-type, 4 microg per ml for mutant with targeted knock-out of efflux pump acrA | Haemophilus influenzae | |
2-amino-N,N-dibenzyl-1,3-oxazole-5-carboxamide | minimal inhibitory concentration 8 microg per ml for wild-type, 4 microg per ml for mutant with targeted knock-out of efflux pump acrA | Moraxella catarrhalis | |
2-amino-N-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-N-(2-methylbenzyl)-1,3-oxazole-5-carboxamide | minimal inhibitory concentration above 64 microg per ml for wild-type, 8 microg per ml for mutant with targeted knock-out of efflux pump tolC and imp gene disruption | Escherichia coli | |
2-amino-N-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-N-(2-methylbenzyl)-1,3-oxazole-5-carboxamide | minimal inhibitory concentration above 64 microg per ml for wild-type, 4 microg per ml for mutant with targeted knock-out of efflux pump acrA | Haemophilus influenzae | |
2-amino-N-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-N-(2-methylbenzyl)-1,3-oxazole-5-carboxamide | minimal inhibitory concentration 16 microg per ml for wild-type, 4 microg per ml for mutant with targeted knock-out of efflux pump acrA | Moraxella catarrhalis | |
6-(2,6-dibromophenyl)pyrido[2,3-d]pyrimidine-2,7-diamine | minimal inhibitory concentration 16 microg per ml for wild-type, 0.125 microg per ml for mutant with targeted knock-out of efflux pump tolC and imp gene disruption | Escherichia coli | |
6-(2,6-dibromophenyl)pyrido[2,3-d]pyrimidine-2,7-diamine | minimal inhibitory concentration 0.125 microg per ml for wild-type, 0.125 microg per ml for mutant with targeted knock-out of efflux pump acrA | Haemophilus influenzae | |
6-(2,6-dibromophenyl)pyrido[2,3-d]pyrimidine-2,7-diamine | minimal inhibitory concentration 1 microg per ml for wild-type, 0.5 microg per ml for mutant with targeted knock-out of efflux pump acrA | Moraxella catarrhalis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | P24182 | - |
- |
Haemophilus influenzae | - |
- |
- |
Moraxella catarrhalis | - |
- |
- |