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Literature summary for 6.3.3.2 extracted from

  • Jeanguenin, L.; Lara-Nunez, A.; Pribat, A.; Mageroy, M.H.; Gregory, J.F.; Rice, K.C.; de Crecy-Lagard, V.; Hanson, A.D.
    Moonlighting glutamate formiminotransferases can functionally replace 5-formyltetrahydrofolate cycloligase (2010), J. Biol. Chem., 285, 41557-41566.
    View publication on PubMedView publication on EuropePMC
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Application

Application Comment Organism
analysis development of a functional complementation assay for 5-CHO-THF metabolism in Escherichia coli, based on deleting the gene encoding 5-FCL. The deletion mutant accumulates 5-formyltetrahydrofolate and,with glycine as sole nitrogen source, shows a growth defect, both phenotypes are complemented by bacterial or archaeal genes encoding glutamate formiminotransferase. Glutamate formiminotransferases functionally replace 5-formyltetrahydrofolate cyclo-ligases in certain prokaryotes Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli A0A061KWR9
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Synonyms

Synonyms Comment Organism
ygfA
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 Escherichia coli