Inhibitors | Comment | Organism | Structure |
---|---|---|---|
10-formylfolic acid | - |
Homo sapiens | |
folic acid | - |
Homo sapiens | |
folic acid pentaglutamate | - |
Homo sapiens | |
folic acid triglutamate | - |
Homo sapiens | |
[6R,S]-10-formyltetrahydrofolate triglutamate | - |
Homo sapiens | |
[6R,S]-10-formyltetrahydrohomofolate | - |
Homo sapiens | |
[6R,S]-10-formyltetrahydropteroate | - |
Homo sapiens | |
[6R,S]-5-formyltetrahydrohomofolate | - |
Homo sapiens | |
[6R]-10-formyltetrahydrofolate | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neuroblastoma cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 5-formyltetrahydrofolate | - |
Homo sapiens | ADP + 5,10-methenyltetrahydrofolate + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Methenyltetrahydrofolate synthetase | - |
Homo sapiens |
MTHFS | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00003 | - |
[6R,S]-10-formyltetrahydrofolate triglutamate | at 37°C in 100 mM MES, pH 6.0 | Homo sapiens | |
0.0001 | - |
folic acid pentaglutamate | at 37°C in 100 mM MES, pH 6.0 | Homo sapiens | |
0.00015 | - |
[6R]-10-formyltetrahydrofolate | at 37°C in 100 mM MES, pH 6.0 | Homo sapiens | |
0.0002 | - |
[6R,S]-10-formyltetrahydrohomofolate | at 37°C in 100 mM MES, pH 6.0 | Homo sapiens | |
0.0007 | - |
[6R,S]-5-formyltetrahydrohomofolate | at 37°C in 100 mM MES, pH 6.0 | Homo sapiens | |
0.0017 | - |
folic acid triglutamate | at 37°C in 100 mM MES, pH 6.0 | Homo sapiens | |
0.005 | - |
[6R,S]-10-formyltetrahydropteroate | at 37°C in 100 mM MES, pH 6.0 | Homo sapiens | |
0.013 | - |
10-formylfolic acid | at 37°C in 100 mM MES, pH 6.0 | Homo sapiens | |
0.058 | - |
folic acid | at 37°C in 100 mM MES, pH 6.0 | Homo sapiens |