KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0008 | - |
(6S)-5-formyltetrahydropteroyl pentaglutamate | mitochondrial enzyme | Homo sapiens | |
0.0047 | - |
(6R,S)-5-formyltetrahydropteroyl-Glu | - |
Homo sapiens | |
0.022 | - |
ATP | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | 85% of the total MTHFS activity is in the cytoplasm | Homo sapiens | 5829 | - |
mitochondrion | matrix | Homo sapiens | 5739 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
25000 | - |
gel filtration, mitochondrial enzyme | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
CA-46 cell | - |
Homo sapiens | - |
liver | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + (6R,S)-5-formyltetrahydropteroyl-Glu | - |
Homo sapiens | ? | - |
? | |
ATP + (6S)-5-formyltetrahydropteroyl-pentaglutamate | - |
Homo sapiens | ? | - |
? | |
ATP + 5-formyltetrahydrofolate | - |
Homo sapiens | ADP + phosphate + 5,10-methylenetetrahydrofolate | - |
? |