Crystallization (Comment) | Organism |
---|---|
moelcular docking of inhibitor 6_3_2-9_4-R16 | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(R,Z)-2-(3-((1-carboxy-N-(4-((4-oxo-2-thioxothiazolidin-5-ylidene)-methyl)phenyl)formamido)methyl)benzamido)pentanedioic acid | - |
Escherichia coli | |
(R,Z)-2-(3-((2-carboxy-N-(4-((4-oxo-2-thioxothiazolidin-5-ylidene)-methyl)phenyl)acetamido)methyl)benzamido)pentanedioic acid | in addition, weak activity against Gram-positive Staphylococcus aureus and Enterococcus faecalis | Escherichia coli | |
(R,Z)-2-(3-((3-carboxy-N-(4-((4-oxo-2-thioxothiazolidin-5-ylidene)-methyl)phenyl)propanamido)methyl)benzamido)pentanedioic acid | in addition, weak activity against Gram-positive Staphylococcus aureus and Enterococcus faecalis | Escherichia coli | |
N-(3-[[(carboxyacetyl)[4-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]phenyl]amino]methyl]benzoyl)-D-glutamic acid | - |
Escherichia coli | |
N-[2-fluoro-5-[([4-[(Z)-(4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]phenyl]amino)methyl]benzoyl]-D-glutamic acid | - |
Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | P14900 | - |
- |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.003 | - |
pH not specified in the publication, temperature not specified in the publication. Malachite green assay in presence of 0.01% Triton X-100 | Escherichia coli | (R,Z)-2-(3-((2-carboxy-N-(4-((4-oxo-2-thioxothiazolidin-5-ylidene)-methyl)phenyl)acetamido)methyl)benzamido)pentanedioic acid | |
0.005 | - |
pH not specified in the publication, temperature not specified in the publication. Malachite green assay in presence of 0.01% Triton X-100 | Escherichia coli | (R,Z)-2-(3-((1-carboxy-N-(4-((4-oxo-2-thioxothiazolidin-5-ylidene)-methyl)phenyl)formamido)methyl)benzamido)pentanedioic acid | |
0.007 | - |
pH not specified in the publication, temperature not specified in the publication. Malachite green assay in presence of 0.01% Triton X-100 | Escherichia coli | (R,Z)-2-(3-((3-carboxy-N-(4-((4-oxo-2-thioxothiazolidin-5-ylidene)-methyl)phenyl)propanamido)methyl)benzamido)pentanedioic acid | |
0.015 | - |
pH not specified in the publication, temperature not specified in the publication. Malachite green assay in presence of 0.01% Triton X-100 | Escherichia coli | N-(3-[[(carboxyacetyl)[4-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]phenyl]amino]methyl]benzoyl)-D-glutamic acid | |
0.252 | - |
pH not specified in the publication, temperature not specified in the publication. Malachite green assay in presence of 0.01% Triton X-100 | Escherichia coli | N-[2-fluoro-5-[([4-[(Z)-(4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]phenyl]amino)methyl]benzoyl]-D-glutamic acid |