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Literature summary for 6.3.2.17 extracted from

  • Leclerc, G.J.; Sanderson, C.; Hunger, S.; Devidas, M.; Barredo, J.C.
    Folylpolyglutamate synthetase gene transcription is regulated by a multiprotein complex that binds the TEL-AML1 fusion in acute lymphoblastic leukemia (2010), Leuk. Res., 34, 1601-1609.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 6.3.2.17

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
acute lymphoblastic leukemia cell
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 Homo sapiens
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acute lymphoblastic leukemia cell line
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 Homo sapiens
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Synonyms

Synonyms Comment Organism
Folylpolyglutamate synthetase
-
 Homo sapiens
FPGS
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 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens both TEL-AML1 and E2A-PBX1 down-regulate FPGS gene transcription through association with this multiprotein complex, and this complex also influences FPGS expression throughout lymphoblast cell cycle progression down