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Literature summary for 6.3.1.10 extracted from

  • Woodson, J.D.; Zayas, C.L.; Escalante-Semerena, J.C.
    A new pathway for salvaging the coenzyme B12 precursor cobinamide in archaea requires cobinamide-phosphate synthase (CbiB) enzyme activity (2003), J. Bacteriol., 185, 7193-7201.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 6.3.1.10

Cloned(Commentary)

Cloned (Comment) Organism
cbiB gene, complementation studies Halobacterium sp.

Protein Variants

Protein Variants Comment Organism
additional information the cbiB in-frame deletion mutant strain JE6791 does not salvage cobinamide Halobacterium sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Halobacterium sp. CbiB is involved in a salvaging pathway for cobinamide ?
-
 ?
additional information Halobacterium sp. NRC-1 CbiB is involved in a salvaging pathway for cobinamide ?
-
 ?

Organism

Organism UniProt Comment Textmining
Halobacterium sp.
-
-
-
Halobacterium sp. NRC-1
-
-
-

Reaction

Reaction Comment Organism Reaction ID
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate = ADP + phosphate + adenosylcobinamide phosphate this enzyme forms part of the anaerobic cobalamin biosynthesis pathway, one of the substrates for this reaction, (R)-1-aminopropan-2-yl phosphate, is produced by CobD, EC 4.1.1.81, threonine phosphate decarboxylase Halobacterium sp.
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
-
 Halobacterium sp. ADP + phosphate + adenosylcobinamide phosphate
-
 ?
ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
-
 Halobacterium sp. NRC-1 ADP + phosphate + adenosylcobinamide phosphate
-
 ?
additional information CbiB is involved in a salvaging pathway for cobinamide Halobacterium sp. ?
-
 ?
additional information CbiB is involved in a salvaging pathway for cobinamide Halobacterium sp. NRC-1 ?
-
 ?

Synonyms

Synonyms Comment Organism
AdoCbi-P synthase
-
 Halobacterium sp.
CbiB
-
 Halobacterium sp.