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Literature summary for 6.3.1.1 extracted from

  • Lorenzi, P.L.; Llamas, J.; Gunsior, M.; Ozbun, L.; Reinhold, W.C.; Varma, S.; Ji, H.; Kim, H.; Hutchinson, A.A.; Kohn, E.C.; Goldsmith, P.K.; Birrer, M.J.; Weinstein, J.N.
    Asparagine synthetase is a predictive biomarker of L-asparaginase activity in ovarian cancer cell lines (2008), Mol. Cancer Ther., 7, 3123-3128.
    View publication on PubMedView publication on EuropePMC

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-aspartate + NH3 Homo sapiens
-
AMP + diphosphate + L-asparagine
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
222 cell
-
Homo sapiens
-
A-224 cell
-
Homo sapiens
-
A-2780 cell
-
Homo sapiens
-
A-364 cell
-
Homo sapiens
-
A-547 cell
-
Homo sapiens
-
AD-10 cell
-
Homo sapiens
-
CAOV-3 cell
-
Homo sapiens
-
IGROV-1 cell an NCI cell line Homo sapiens
-
additional information DNA fingerprinting in ovarian cancer cell lines, overview Homo sapiens
-
ovarian cancer cell enzyme expression analysis in 19 human ovarian cell lines, overview Homo sapiens
-
ovarian cancer cell line of the NCI-60 cell line panel Homo sapiens
-
OVCAR-3 cell
-
Homo sapiens
-
OVCAR-4 cell an NCI cell line Homo sapiens
-
OVCAR-420 cell
-
Homo sapiens
-
OVCAR-429 cell
-
Homo sapiens
-
OVCAR-8 cell an NCI cell line Homo sapiens
-
OVCAR-8/ADR cell an NCI cell line Homo sapiens
-
SKOV-3 cell an NCI cell line Homo sapiens
-
UCI-101 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-aspartate + NH3
-
Homo sapiens AMP + diphosphate + L-asparagine
-
?

Synonyms

Synonyms Comment Organism
ASNS
-
Homo sapiens
Asparagine synthetase
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
Homo sapiens