Cloned (Comment) | Organism |
---|---|
gene fadD1, DNA and amino acid sequence determination, genetic organization, complemention of Escherichia coli strain fadD-/fadR- strain E2011. SMART mapping of the transcriptional start site for fadD1 | Pseudomonas aeruginosa |
gene fadD2, DNA and amino acid sequence determination, genetic organization, complemention of Escherichia coli strain fadD-/fadR- strain E2011. SMART mapping of the transcriptional start site fadD1 | Pseudomonas aeruginosa |
Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of fadD1 mutants, phenotype, overview | Pseudomonas aeruginosa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Pseudomonas aeruginosa | FadD1 has a substrate preference for long-chain fatty acids, while FadD2 prefers shorter-chain fatty acids | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas aeruginosa | Q9HYU3 | FadD2; gene FadD2 | - |
Pseudomonas aeruginosa | Q9HYU4 | FadD1; gene FadD1 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | FadD1 has a substrate preference for long-chain fatty acids, while FadD2 prefers shorter-chain fatty acids | Pseudomonas aeruginosa | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | FadDs contain ATP/AMP signature and FA-binding motifs | Pseudomonas aeruginosa |
Synonyms | Comment | Organism |
---|---|---|
Acyl-CoA synthetase | - |
Pseudomonas aeruginosa |
FAdD | - |
Pseudomonas aeruginosa |
General Information | Comment | Organism |
---|---|---|
malfunction | when compared to the wild-type strain, the fadD2 mutant exhibits decreased production of lipase, protease, rhamnolipid and phospholipase, and retardation of both swimming and swarming motilities. Interestingly, fadD1 mutant shows only increased swarming motility. Growth analysis of the fadD mutants show noticeable deficiencies in utilizing fatty acids and phosphatidylcholine as the sole carbon source, altered swimming and swarming motility of fadD mutants | Pseudomonas aeruginosa |