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Literature summary for 6.2.1.3 extracted from
- Long chain acyl-CoA synthetase 3-mediated phosphatidylcholine synthesis is required for assembly of very low density lipoproteins in human hepatoma Huh7 cells (2007), J. Biol. Chem., 283, 849-854.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Triacsin C | 95% inhibition at 0.005 mM | Homo sapiens |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| vesicle | - |
Homo sapiens | 31982 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | O60488 | - |
- |
| Homo sapiens | O95573 | - |
- |
| Homo sapiens | P33121 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| hepatoma cell | - |
Homo sapiens | - |
| Huh-7 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + oleate + CoA | - |
Homo sapiens | AMP + diphosphate + oleoyl-CoA | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ACSL1 | - |
Homo sapiens |
| ACSL3 | specifically required for incorporation of fatty acids into phosphatidylcholine | Homo sapiens |
| ACSL4 | - |
Homo sapiens |
| long chain acyl-CoA synthetase 3 | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Homo sapiens | |
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Release 2023.1 (January 2023)
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