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Literature summary for 6.2.1.3 extracted from

  • De Jong, H.; Neal, A.C.; Coleman, R.A.; Lewin, T.M.
    Ontogeny of mRNA expression and activity of long-chain acyl-CoA synthetase (ACSL) isoforms in Mus musculus heart (2007), Biochim. Biophys. Acta, 1771, 75-82.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 6.2.1.3

Inhibitors

Inhibitors Comment Organism Structure
arachidonate inhibits palmitoyl-CoA synthesis at high concentrations Mus musculus
additional information not inhibited by thiazolidinediones; not inhibited by thiazolidinediones; not inhibited by triacsin C; not inhibited by triacsin C; not inhibited by triacsin C Mus musculus
thiazolidinediones
-
 Mus musculus
Triacsin C
-
 Mus musculus
troglitazone 0.05 mM, 5% inhibition Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus P41216
-
-
Mus musculus Q8JZR0
-
-
Mus musculus Q91WC3
-
-
Mus musculus Q9CZW4
-
-
Mus musculus Q9QUJ7
-
-

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + arachidonate + CoA
-
 Mus musculus AMP + diphosphate + arachidonoyl-CoA
-
 ?
ATP + eicosapentaenoate + CoA
-
 Mus musculus AMP + diphosphate + eicosapentaenoyl-CoA
-
 ?
ATP + laurate + CoA
-
 Mus musculus AMP + diphosphate + lauroyl-CoA
-
 ?
ATP + myristate + CoA
-
 Mus musculus AMP + diphosphate + myristoyl-CoA
-
 ?
ATP + palmitate + CoA
-
 Mus musculus AMP + diphosphate + palmitoyl-CoA
-
 ?

Synonyms

Synonyms Comment Organism
ACSL1
-
 Mus musculus
ACSL3
-
 Mus musculus
ACSL4
-
 Mus musculus
ACSL5
-
 Mus musculus
ACSL6
-
 Mus musculus
long-chain acyl-CoA synthetase
-
 Mus musculus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Mus musculus