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Literature summary for 6.2.1.20 extracted from

  • Kaczmarzyk, D.; Fulda, M.
    Fatty acid activation in cyanobacteria mediated by acyl-acyl carrier protein synthetase enables fatty acid recycling (2010), Plant Physiol., 152, 1598-1610.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
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Synechocystis sp.
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Synechococcus elongatus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.01
-
oleic acid pH 8.0 Synechococcus elongatus

Organism

Organism UniProt Comment Textmining
Synechococcus elongatus Q31PS1 PCC 7942
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Synechocystis sp.
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PCC 6803
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + oleic acid + [acyl-carrier protein]
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Synechococcus elongatus AMP + diphosphate + oleoyl-[acyl-carrier protein]
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?
additional information rather broad substrate specificity, accepting fatty acids with chain length between C12 and C18 Synechococcus elongatus ?
-
?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.016
-
oleic acid pH 8.0 Synechococcus elongatus

General Information

General Information Comment Organism
physiological function knockout mutant strains show two phenotypes characterized by the inability to utilize exogenous fatty acids and by the secretion of endogenous fatty acids into the culture medium. The detected free fatty acids are released from membrane lipids. The data suggest a considerable turnover of lipid molecules and a role for Aas activity in recycling the released fatty acids Synechocystis sp.
physiological function knockout mutant strains show two phenotypes characterized by the inability to utilize exogenous fatty acids and by the secretion of endogenous fatty acids into the culture medium. The detected free fatty acids are released from membrane lipids. The data suggest a considerable turnover of lipid molecules and a role for Aas activity in recycling the released fatty acids Synechococcus elongatus