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Literature summary for 6.2.1.1 extracted from
- Unraveling the structure and mechanism of acetyl-coenzyme A synthase (2004), Acc. Chem. Res., 37, 775-783.
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ni | nickel-containing bimetallic site, the bifunctional enzyme carbon monoxide dehydrogenase/acetyl-coenzyme A synthase | Moorella thermoacetica |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + acetate + CoA | Moorella thermoacetica | the bifunctional enzyme carbon monoxide dehydrogenase/acetyl-coenzyme A synthase is a key enzyme in the Wood-Ljungdahl pathway of carbon fixation | AMP + diphosphate + acetyl-CoA | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Moorella thermoacetica | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + acetate + CoA | the bifunctional enzyme carbon monoxide dehydrogenase/acetyl-coenzyme A synthase is a key enzyme in the Wood-Ljungdahl pathway of carbon fixation | Moorella thermoacetica | AMP + diphosphate + acetyl-CoA | - |
? | |
| ATP + acetate + CoA | proposed mechanism of the bifunctional enzyme carbon monoxide dehydrogenase/acetyl-coenzyme A synthase | Moorella thermoacetica | AMP + diphosphate + acetyl-CoA | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| carbon monoxide dehydrogenase/acety-coenzyme A synthase | bifunctional enzyme | Moorella thermoacetica |
| CODH/ACS | bifunctional enzyme | Moorella thermoacetica |
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Release 2023.1 (January 2023)
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