Literature summary for 6.2.1.1 extracted from

Kumari, S.; Beatty, C.M.; Browning, D.F.; Busby, S.J.W.; Simel, E.J.; Hovel-Miner, G.; Wolfe, A.J.
Regulation of acetyl coenzyme A synthetase in Escherichia coli (2000), J. Bacteriol., 182, 4173-4179.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + acetate + CoA	Escherichia coli	enzyme is involved in pathway of acetate activation. Cells induce acs transcription, and thus the ability to assimilate acetate, in response to rising cAMP levels, falling oxygen partial pressure, and the flux of carbon through pathways associated with acetate metabolism	AMP + diphosphate + acetyl-CoA	-	?

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + acetate + CoA	enzyme is involved in pathway of acetate activation. Cells induce acs transcription, and thus the ability to assimilate acetate, in response to rising cAMP levels, falling oxygen partial pressure, and the flux of carbon through pathways associated with acetate metabolism	Escherichia coli	AMP + diphosphate + acetyl-CoA	-	?

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Release 2023.1 (January 2023)