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BRENDA support

Literature summary for 6.1.1.5 extracted from

  • Glasfeld, E.; Landro, J.A.; Schimmel, P.
    C-terminal zinc-containing peptide required for RNA recognition by a class I tRNA synthetase (1996), Biochemistry, 35, 4139-4145.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00028
-
ATP
-
Escherichia coli
0.0036
-
Ile
-
Escherichia coli

Metals/Ions

Metals/Ions Comment Organism Structure
Zinc required Escherichia coli
Zinc bound to a Cys4 cluster at the C-terminal end of the polypeptide Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-isoleucine + tRNAIle
-
Escherichia coli AMP + diphosphate + L-isoleucyl-tRNAIle
-
?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
80.4
-
ATP wild-type enzyme Escherichia coli