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Literature summary for 6.1.1.21 extracted from
- Purification of bovine liver histidyl-tRNA synthetase, the Jo-1 antigen of polymyositis (1987), Biol. Chem. Hoppe-Seyler, 368, 531-537.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | the autoantibody anti-Jo-1 is a useful diagnostic tool since the antibody is very specific for polymyositis | Bos taurus |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 80000 | - |
2 * 80000, SDS-PAGE | Bos taurus |
| 160000 | - |
electrophoresis under nondenaturing conditions | Bos taurus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Bos taurus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Bos taurus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + L-histidine + tRNAHis | - |
Bos taurus | AMP + diphosphate + L-histidyl-tRNAHis | - |
? |  |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 80000, SDS-PAGE | Bos taurus |
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Release 2023.1 (January 2023)
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