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Literature summary for 6.1.1.20 extracted from

  • Kekenes-Huskey, P.M.; Vaidehi, N.; Floriano, W.B.; Goddard, W.A.
    Fidelity of Phenylalanyl-tRNA Synthetase in Binding the Natural Amino Acids (2003), J. Phys. Chem. B, 107, 11549-11557.
No PubMed abstract available
Search for more literature for 6.1.1.20

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information kinetics, binding energies in the active conformation Thermus thermophilus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-phenylalanine + tRNAPhe Thermus thermophilus
-
 AMP + diphosphate + L-phenylalanyl-tRNAPhe
-
 r

Organism

Organism UniProt Comment Textmining
Thermus thermophilus
-
-
-

Reaction

Reaction Comment Organism Reaction ID
ATP + L-phenylalanine + tRNAPhe = AMP + diphosphate + L-phenylalanyl-tRNAPhe substrate binding mechanism, residues S180, Q218, E220, W149, H178, R204, and Q218 are involved in binding of phenylalanine via hydrogen bonds Thermus thermophilus
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-phenylalanine + tRNAPhe
-
 Thermus thermophilus AMP + diphosphate + L-phenylalanyl-tRNAPhe
-
 r
ATP + L-phenylalanine + tRNAPhe reaction intermediate aminacyl-AMP stucture Thermus thermophilus AMP + diphosphate + L-phenylalanyl-tRNAPhe
-
 r

Synonyms

Synonyms Comment Organism
CML33
-
 Thermus thermophilus
FRS
-
 Thermus thermophilus
HSPC173
-
 Thermus thermophilus
L-Phenylalanyl-tRNA synthetase
-
 Thermus thermophilus
Phenylalanine translase
-
 Thermus thermophilus
Phenylalanine--tRNA ligase
-
 Thermus thermophilus
Phenylalanine-tRNA synthetase
-
 Thermus thermophilus
Phenylalanyl transfer ribonucleic acid synthetase
-
 Thermus thermophilus
Phenylalanyl-transfer ribonucleate synthetase
-
 Thermus thermophilus
Phenylalanyl-transfer RNA ligase
-
 Thermus thermophilus
Phenylalanyl-transfer RNA synthetase
-
 Thermus thermophilus
Phenylalanyl-tRNA ligase
-
 Thermus thermophilus
Phenylalanyl-tRNA synthetase
-
 Thermus thermophilus
PheRS
-
 Thermus thermophilus
Synthetase, phenylalanyl-transfer ribonucleate
-
 Thermus thermophilus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Thermus thermophilus