Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-Selenaproline | competitive | Escherichia coli | |
3-Selenaproline | competitive | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.4 | - |
Pro | ATP-diphosphate exchange | Rattus norvegicus | |
0.8 | - |
Pro | 3-thiaproline, , ATP-diphosphate exchange | Escherichia coli | |
1.4 | - |
3-thiaproline | ATP-diphosphate exchange | Rattus norvegicus | |
6.25 | - |
2-selenaproline | ATP-diphosphate exchange | Rattus norvegicus | |
12.5 | - |
gamma-thiaproline | ATP-diphosphate exchange | Rattus norvegicus | |
66 | - |
4-thiaproline | ATP-diphosphate exchange | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 2-selenaproline + tRNAPro | - |
Rattus norvegicus | ? | - |
? | |
ATP + 3-thiaproline + tRNAPro | - |
Rattus norvegicus | ? | - |
? | |
ATP + gamma-thiaproline + tRNAPro | - |
Rattus norvegicus | ? | - |
? | |
ATP + L-proline + tRNAPro | - |
Escherichia coli | AMP + diphosphate + L-prolyl-tRNAPro | - |
? | |
ATP + L-proline + tRNAPro | - |
Rattus norvegicus | AMP + diphosphate + L-prolyl-tRNAPro | - |
? | |
additional information | ATP-diphosphate exchange | Escherichia coli | ? | - |
? | |
additional information | ATP-diphosphate exchange | Rattus norvegicus | ? | - |
? | |
additional information | 3-thiaproline, 4-thiaproline and 4-selenaproline can replace proline in the ATP-diphosphate exchange. 4-Thiaproline and 4-selenaproline show a much higher Km | Escherichia coli | ? | - |
? | |
additional information | 3-thiaproline, 4-thiaproline and 4-selenaproline can replace proline in the ATP-diphosphate exchange. 4-Thiaproline and 4-selenaproline show a much higher Km | Rattus norvegicus | ? | - |
? |