Activating Compound | Comment | Organism | Structure |
---|---|---|---|
3-deoxy-D-arabino-heptulosonate-7-phosphate synthase | - |
Mycobacterium tuberculosis |
Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli strain KA13 | Mycobacterium tuberculosis |
Crystallization (Comment) | Organism |
---|---|
alone and in complex with 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, hanging drop vapor diffusion method, using 25% (w/v) PEG 1500 and 0.1 M MMT buffer (L-malic acid, MES, Tris) pH 8.0-9.0 | Mycobacterium tuberculosis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | P9WIC1 | - |
- |
Mycobacterium tuberculosis H37Rv | P9WIC1 | - |
- |
Purification (Comment) | Organism |
---|---|
ammonium sulfate precipitation, Ni-NTA agarose column chromatography, and Superdex 75 gel filtration | Mycobacterium tuberculosis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Chorismate | the enzyme catalyzes the Claisen rearrangement of chorismate to prephenate | Mycobacterium tuberculosis | Prephenate | - |
? | |
Chorismate | the enzyme catalyzes the Claisen rearrangement of chorismate to prephenate | Mycobacterium tuberculosis H37Rv | Prephenate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Rv0948c | - |
Mycobacterium tuberculosis |