Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | a thiol is required for maximum activity | Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Calf thymus DNA | native and denatured, about 66% residual activity | Bos taurus | |
poly(rA)n | 71% residual acivity | Bos taurus | |
poly(rC)n | 93% residual acivity | Bos taurus | |
poly(rG)n | 3.2% residual acivity | Bos taurus | |
poly(rI)n | 11.9% residual acivity | Bos taurus | |
poly(rU)n | 44% residual acivity | Bos taurus | |
tRNA | activity is inhibited by single tRNAs or bulk tRNA from all sources tested, and by ribosomal RNA | Bos taurus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | a monovalent cation is required for maximum activity | Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
steer | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
thymus | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Salmonella typhimurium HisT- tRNALeu | tRNAPhe2 from mutant HisT- strain defective for tRNA pseudouridine synthase I that forms pseudouridine in the 3'-side of the anticodon region of approximately half of the cellular tRNAs | Bos taurus | ? | - |
? | |
Salmonella typhimurium HisT- tRNAPhe2 uridine39 | tRNAPhe2 from mutant HisT- strain defective for tRNA pseudouridine synthase I that forms pseudouridine in the 3 side of the anticodon region of approximately half of the cellular tRNAs | Bos taurus | Salmonella typhimurium HisT- tRNAPhe2 pseudouridine39 | specific modification of uridine39 | ? | |
Salmonelly typhimurium HisT- tRNATyr | tRNAPhe2 from mutant HisT- strain defective for tRNA pseudouridine synthase I that forms pseudouridine in the 3'-side of the anticodon region of approximately half of the cellular tRNAs | Bos taurus | ? | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
additional information | no cofactors required | Bos taurus |