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Literature summary for 5.4.2.4 extracted from
- Purification and properties of 2,3-bisphosphoglycerate phosphatase-mutase from erythrocytes of day-old chicks (1977), Eur. J. Biochem., 78, 343-351.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| 2-Phosphoglycolate | 0.02 mM activates | Gallus gallus |  |
| phosphoenolpyruvate | stimulation | Gallus gallus | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2-phosphoglycerate | - |
Gallus gallus | |
| 3-phosphoglycerate | - |
Gallus gallus | |
| diphosphate | - |
Gallus gallus | |
| phytic acid | i.e. inositol hexaphosphate | Gallus gallus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0024 | - |
2,3-diphosphoglycerate | presence of activator 2-phosphoglycolate | Gallus gallus | |
| 0.0028 | - |
2,3-diphosphoglycerate | absence of activator 2-phosphoglycolate | Gallus gallus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Na2S2O4 | stimulation | Gallus gallus | |
| NaHSO3 | stimulation | Gallus gallus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Gallus gallus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| copurification of EC 5.4.2.1 (phosphoglycerate mutase) and EC 3.1.3.13 (bisphosphoglycerate phosphatase), three activities in one enzyme protein | Gallus gallus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| erythrocyte | embryonic | Gallus gallus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.56 | - |
- |
Gallus gallus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1,3-Diphosphoglycerate | the enzyme has additional activities of EC 5.4.2.1(phosphoglycerate mutase) and EC 3.1.3.13 (bisphosphoglycerate phosphatase) | Gallus gallus | 2,3-Diphosphoglycerate | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
- |
Gallus gallus |
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