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Literature summary for 5.4.2.2 extracted from

  • Howard, S.C.; Deminoff, S.J.; Herman, P.K.
    Increased phosphoglucomutase activity suppresses the galactose growth defect associated with elevated levels of Ras signaling in S. cerevisiae (2006), Curr. Genet., 49, 1-6.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information overexpression of phosphoglucomutase gene PGM1 is able to suppress the growth-deficiency of mutant RAS2val19 that is unable to grow on galactose as the sole source of carbon. Elevated levels of enzyme allow for the more efficient utilization of the limiting levels of glucose 1-phosphate that are present in the RASval19 mutant Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
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