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Literature summary for 5.4.2.2 extracted from
- Regulation of glucosylation of teichoic acid. II. Partial characterization of phosphoglucomutase in Bacillus subtilis 168 (1974), J. Biol. Chem., 249, 5176-5181.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| alpha-D-glucose 1,6-diphosphate | Km: 0.00053 mM phosphoglucomutase I, 0.00232 mM, phosphoglucomutase II | Bacillus subtilis |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Bacillus subtilis | |
| CTP | - |
Bacillus subtilis | |
| fructose 1,6-diphosphate | - |
Bacillus subtilis | |
| GTP | - |
Bacillus subtilis | |
| UTP | - |
Bacillus subtilis | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | 20-100 mM, activation of phosphoglucomutase I and II | Bacillus subtilis | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 60000 | - |
2 * 60000, SDS-PAGE | Bacillus subtilis |
| 130000 | - |
phosphoglucomutase I and II, gel filtration | Bacillus subtilis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus subtilis | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| alpha-D-glucose 1-phosphate | - |
Bacillus subtilis | alpha-D-glucose 6-phosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 60000, SDS-PAGE | Bacillus subtilis |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 50 | - |
phosphoglucomutase I, 30 min, 50% loss of activity, 80 min, 75% loss of activity | Bacillus subtilis |
| 50 | - |
phosphoglucomutase II, 15 min, 50% loss of activity, 80 min, 95% loss of activity | Bacillus subtilis |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.1 | - |
phosphoglucomutase I and II | Bacillus subtilis |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | 9 | phosphoglucomutase I | Bacillus subtilis |
| 7.5 | 8.6 | phosphoglucomutase II | Bacillus subtilis |
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