Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CaCl2 | mild | Homo sapiens | |
CdCl2 | moderate | Homo sapiens | |
CuCl2 | strong | Homo sapiens | |
FeCl2 | moderate | Homo sapiens | |
ZnCl2 | moderate | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0093 | - |
5-Pregnene-3,20-dione | - |
Homo sapiens | |
0.0276 | - |
5-androstene-3,17-dione | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Homo sapiens | - |
- |
mitochondrion | - |
Homo sapiens | 5739 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
41000 | - |
2 * 41000, SDS-PAGE | Homo sapiens |
77000 | - |
enzyme complex of 3beta-hydroxy-5-ene-steroid dehydrogenase and steroid DELTA-isomerase gel filtration | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
enzyme complex of 3beta-hydroxy-5-ene-steroid dehydrogenase and Steroid DELTA-isomerase | - |
Purification (Comment) | Organism |
---|---|
enzyme complex of 3beta-hydroxy-5-ene-steroid dehydrogenase and steroid 5 to 4 isomerase | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
placenta | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Homo sapiens |
Storage Stability | Organism |
---|---|
-20°C, 4.3% loss of activity after 2 weeks | Homo sapiens |
-70°C, 6 months, no loss of activity | Homo sapiens |
22°C, 31.5% loss of activity after 4 days | Homo sapiens |
4°C, 12.5% loss of activity after 7 days | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5-Androstene-3,17-dione | - |
Homo sapiens | 4-Androstene-3,17-dione | - |
? | |
5-Pregnene-3,20-dione | - |
Homo sapiens | 4-Pregnene-3,20-dione | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 41000, SDS-PAGE | Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
- |
Homo sapiens |
Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|
22 | 42 | 22°C: about 60% of maximal activity, 40°C: about 40% of maximal activity | Homo sapiens |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
22 | - |
31.5% loss of activity after 4 days | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
- |
Homo sapiens |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6.5 | 8 | pH 6.5: about 60% of maximal activity, pH 8.0: about 40% of maximal activity, pH 6.3: no activity | Homo sapiens |